SCHEMBL644797

SCHEMBL644797

C=CCOc1cc(C(=O)O)cc(C(=O)O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.49
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
KDM4E B2RXH2 2/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
PLA2G2A P14555 1/20 0.46
GAA P10253 1/20 0.45
TSHR P16473 1/20 0.45
ALDH1A1 P00352 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
MAPT P10636 3/20 0.41
POLB P06746 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
PKM P14618 1/20 0.41
LMNA P02545 1/20 0.40
KAT6A Q92794 1/20 0.40
HTT P42858 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20838307 0.96 MEN1 (0.51) FFAR1NPC1RAB9AKDM4EMEN1
SCHEMBL4880394 0.92 FFAR1 (0.44) FFAR1NPC1RAB9AKDM4EMEN1
SCHEMBL2526307 0.92 FFAR1 (0.44) FFAR1NPC1RAB9AKDM4EMEN1
SCHEMBL4879486 0.90 GPBAR1 (0.51) FFAR1NPC1RAB9AKDM4EMEN1
SCHEMBL2525888 0.89 FFAR1 (0.45) FFAR1NPC1RAB9AKDM4EMEN1
SCHEMBL4878837 0.88 PLA2G2A (0.47) FFAR1NPC1RAB9AKDM4EMEN1
SCHEMBL18311238 0.88 KAT6A (0.52) FFAR1NPC1RAB9AKDM4EMEN1
SCHEMBL2527537 0.87 FFAR1 (0.41) FFAR1NPC1RAB9AKDM4EMEN1
SCHEMBL4877310 0.87 FFAR1 (0.43) FFAR1NPC1RAB9AKDM4EMEN1
SCHEMBL4874108 0.86 CYP2C9 (0.50) FFAR1NPC1RAB9AKDM4EPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120005563-A Anti-precipitation heat conduction pouring sealant and preparation method thereof 广东施奈仕实业有限公司 2025-05-16 CN claimed
CN-117736370-B Thickening tackifier for temperature-resistant polyacrylamide fracturing fluid and preparation method thereof 东营江源化工有限公司 2024-05-03 CN claimed
CN-117736370-A Thickening tackifier for temperature-resistant polyacrylamide fracturing fluid and preparation method thereof 东营江源化工有限公司 2024-03-22 CN claimed
CN-120005563-A Anti-precipitation heat conduction pouring sealant and preparation method thereof 广东施奈仕实业有限公司 2025-05-16 CN disclosed
US-11999716-B2 WDR5 inhibitors and modulators VANDERBILT UNIVERSITY (US) 2024-06-04 US disclosed
CN-117384077-A Novel polymer, diamine compound, liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2024-01-12 CN disclosed
CN-117384078-A Novel polymer, diamine compound, liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2024-01-12 CN disclosed
CN-117384076-A Novel polymer, diamine compound, liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2024-01-12 CN disclosed
US-20230012362-A1 WDR5 INHIBITORS AND MODULATORS VANDERBILT UNIVERSITY 2023-01-12 US disclosed
CN-114384756-A Resin composition, toner for developing electrostatic image, image forming method, photosensitive adhesive, and photoswitch material 柯尼卡美能达株式会社 2022-04-22 CN disclosed
US-20220107576-A1 RESIN COMPOSITION, TONER FOR DEVELOPING ELECTROSTATIC CHARGE IMAGE, IMAGE FORMING METHOD, PHOTOSENSITIVE ADHESIVE, AND OPTICAL SWITCHING MATERIAL Konica Minolta, Inc. (JP) 2022-04-07 US disclosed
US-7842713-B2 Fused phenyl amido heterocyclic compounds PFIZER INC (US) 2010-11-30 US disclosed
EP-2010520-A1 FUSED PHENYL AMIDO HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOKINASE-MEDIATED DISEASES Pfizer Products Incorporated (US) 2009-01-07 EP disclosed
US-20080280875-A1 FUSED PHENYL AMIDO HETEROCYCLIC COMPOUNDS PFIZER INC. 2008-11-13 US disclosed
WO-2007122482-A1 FUSED PHENYL AMIDO HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOKINASE-MEDIATED DISEASES PFIZER PRODUCTS INC. (US) 2007-11-01 WO disclosed
US-6808766-B1 ALIGNMENT AGENT COMPRISING POLYURETHANE OR POLYUREA, USED IN ALIGNMENT OF LIQUID CRYSTAL MOLECULES THAT FORM LIQUID CRYSTAL ALIGNMENT FILM BY IRRADIATING THIN ALIGNMENT FILM FORMED ON SUBSTRATE WITH POLARIZED LIGHT OR ELECTRON RAYS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-10-26 US disclosed
EP-1111442-A1 TREATING AGENT FOR LIQUID CRYSTAL ALIGNMENT LAYER AND LIQUID CRYSTAL DEVICE USING THE SAME, AND METHOD FOR ALIGNMENT OF LIQUID CRYSTAL Nissan Chemical Industries, Ltd. (JP) 2001-06-27 EP disclosed
US-4975490-A Phthalic acid ester-modified organopolysiloxane and method for its preparation TORAY SILICONE COMPANY, LTD. (JP) 1990-12-04 US disclosed
US-4924020-A Phthalic acid ester-modified organopolysiloxane and method for its preparation TORAY SILICON COMPANY, LTD. (JP) 1990-05-08 US disclosed
EP-0316915-A2 Phthalic acid ester-modified organopolysiloxane and method for its preparation TORAY SILICONE COMPANY, LIMITED (JP) 1989-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230012362-A1 WDR5 INHIBITORS AND MODULATORS WDR5, WDR1, WDR77 FFAR1 4457/4885NPC1 1581/4885RAB9A 1954/4885
US-11999716-B2 WDR5 inhibitors and modulators WDR5, WDR1, WDR3 FFAR1 4397/4885NPC1 1503/4885RAB9A 1969/4885
US-20080280875-A1 FUSED PHENYL AMIDO HETEROCYCLIC COMPOUNDS GCK, GCKR, HK1 FFAR1 1577/4885NPC1 1969/4885RAB9A 2949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.