Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448975 | 0.83 | ALDH1A1 (0.39) | ALDH1A1BCHEACHE | |
| SCHEMBL20487794 | 0.80 | GNAO1 (0.46) | ALDH1A1CHRM1 | |
| SCHEMBL9741247 | 0.80 | GNAO1 (0.46) | ALDH1A1CHRM1 | |
| SCHEMBL6446594 | 0.80 | LSS (0.38) | — | |
| SCHEMBL4239877 | 0.78 | GNAO1 (0.43) | ALDH1A1CHRM1 | |
| Hydrochloric Acid SCHEMBL5035531 | 0.78 | LSS (0.46) | — | |
| SCHEMBL6132345 | 0.77 | SLC6A4 (0.34) | ALDH1A1 | |
| SCHEMBL6132360 | 0.77 | SLC6A4 (0.34) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27157910 | 0.77 | GNAO1 (0.46) | ALDH1A1CHRM1 | |
| SCHEMBL27528376 | 0.77 | SLC6A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6964974-B2 | 2,3-oxidosqualene-lanosterol cyclase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2005-11-15 | — | — | US | disclosed |