Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6449276 | 0.85 | LSS (0.51) | LSS | |
| Hydrochloric Acid SCHEMBL5045765 | 0.84 | LSS (0.50) | LSS | |
| SCHEMBL6448156 | 0.80 | ALDH1A1 (0.36) | — | |
| SCHEMBL6448975 | 0.76 | ALDH1A1 (0.39) | LSS | |
| SCHEMBL9723824 | 0.74 | SLC2A1 (0.38) | — | |
| SCHEMBL27528376 | 0.73 | SLC6A2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL5040217 | 0.72 | SLC6A2 (0.32) | — | |
| SCHEMBL3186641 | 0.71 | SLC6A2 (0.37) | — | |
| SCHEMBL27499331 | 0.71 | SLC6A2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL5035531 | 0.71 | LSS (0.46) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6964974-B2 | 2,3-oxidosqualene-lanosterol cyclase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2005-11-15 | — | — | US | disclosed |