Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445952 | 0.75 | ALDH1A1 (0.38) | ALDH1A1NOTUMCTDSP1MEN1KMT2A | |
| SCHEMBL6442621 | 0.73 | NOTUM (0.36) | ALDH1A1NOTUMCYP1A2SMN1; SMN2HPGD | |
| SCHEMBL6443441 | 0.67 | — | — | |
| SCHEMBL10205955 | 0.62 | ALDH1A1 (0.43) | ALDH1A1NOTUMMEN1KMT2ARAB9A | |
| SCHEMBL6446839 | 0.62 | ALDH1A1 (0.40) | ALDH1A1NOTUMMEN1KMT2ARAB9A | |
| SCHEMBL17589460 | 0.61 | ALDH1A1 (0.44) | ALDH1A1NOTUMMEN1KMT2ARAB9A | |
| SCHEMBL6455198 | 0.60 | NOTUM (0.36) | ALDH1A1NOTUMCYP1A2SMN1; SMN2HPGD | |
| SCHEMBL5857932 | 0.60 | ALDH1A1 (0.58) | ALDH1A1NOTUMMEN1KMT2ARAB9A | |
| SCHEMBL9370346 | 0.60 | POLB (0.64) | ALDH1A1NOTUMMEN1KMT2ALMNA | |
| SCHEMBL65301 | 0.60 | MAPT (0.54) | ALDH1A1NOTUMMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949614-B1 | Catalyst system | BASELL POLYOLEFINE GMBH (DE) | 2005-09-27 | — | — | US | disclosed |
| EP-1272532-B1 | SALINE CHEMICAL COMPOSITION, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2005-05-04 | — | — | EP | disclosed |
| EP-1054914-B1 | ZWITTERIONIC, NEUTRAL TRANSITION METAL COMPOUND | BASELL POLYOLEFINE GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| EP-1175262-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2004-02-18 | — | — | EP | disclosed |
| EP-1290002-B1 | CHEMICAL PRODUCTS SUITED FOR USE AS CO-CATALYSTS, METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-01-21 | — | — | EP | disclosed |