SCHEMBL65301

SCHEMBL65301

Cc1ccc(C)n1-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.54
ALDH1A1 P00352 8/20 0.54
KDM4E B2RXH2 8/20 0.54
MEN1 O00255 6/20 0.54
KMT2A Q03164 6/20 0.54
ALOX15 P16050 3/20 0.54
POLB P06746 3/20 0.54
TDP1 Q9NUW8 2/20 0.54
HPGD P15428 2/20 0.54
APEX1 P27695 1/20 0.54
CASP1 P29466 1/20 0.54
CASP7 P55210 1/20 0.54
USP2 O75604 3/20 0.52
NR4A1 P22736 2/20 0.52
HSD17B10 Q99714 2/20 0.52
GAA P10253 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
MYC P01106 1/20 0.52
HSPA1A P0DMV8 1/20 0.52
PTPN7 P35236 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10205946 0.81 ALDH1A1 (0.69) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL17916172 0.79 PTGS2 (0.44) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL17916173 0.79 CYP1A2 (0.40) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL3970588 0.79 GSK3A (0.47) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL17172442 0.78 NOTUM (0.50) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL21363125 0.78 ALDH1A1 (0.55) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL3547671 0.78 ATM (0.46) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL9370346 0.78 POLB (0.64) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL13543619 0.77 MAPT (0.58) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL12799580 0.76 PTGS2 (0.66) MAPTALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103756740-B Vehicle methanol fuel corrosion-inhibitor for various metals SHAANXI YCZL NEW ENERGY CO LTD 2015-05-20 CN claimed
CN-119569634-A Process for the preparation of N-substituted pyrrole compounds 中国石油化工股份有限公司 2025-03-07 CN disclosed
CN-119570046-A Modified metal organic framework material and preparation method and application thereof 中国石油化工股份有限公司 2025-03-07 CN disclosed
CN-119570045-A Copper-iron bimetallic MOFs material, preparation method and application thereof, and method for preparing N-substituted pyrrole compound 中国石油化工股份有限公司 2025-03-07 CN disclosed
CN-118184564-A Method for synthesizing 2, 5-dimethyl-N-aryl pyrrole compound 浙江工业大学 2024-06-14 CN disclosed
CN-117603119-A Preparation of cation free radical-based gene delivery system and application thereof in pancreatic cancer treatment 华南理工大学 2024-02-27 CN disclosed
CN-117603119-A Preparation of cation free radical-based gene delivery system and application thereof in pancreatic cancer treatment 华南理工大学 2024-02-27 CN disclosed
CN-112165936-B beta-lactamase inhibitor 国立大学法人东海国立大学机构 2023-11-28 CN disclosed
US-11746098-B2 Proteasome activity enhancing compounds PROTEOSTASIS THERAPEUTICS, INC. (US) 2023-09-05 US disclosed
US-11746098-B2 Proteasome activity enhancing compounds PROTEOSTASIS THERAPEUTICS, INC. (US) 2023-09-05 US disclosed
US-5274072-A A 2-amine-containing methylene-2,5-dihydrofur-5-one EASTMAN KODAK COMPANY (US) 1993-12-28 US disclosed
US-4273713-A ANTIULCER AND ANTISECRETORY AGENTS STERLING DRUG INC. (US) 1981-06-16 US disclosed
US-4248784-A Pyrrole-3-acetamides STERLING DRUG INC. (US) 1981-02-03 US disclosed
US-4239687-A 4-CARBOXAMIDES, 4-THIOCARBOXAMIDES, 4-NITRILES, ANTISECRETORY, ANTIULCER STERLING DRUG INC. (US) 1980-12-16 US disclosed
US-4140854-A ANTISECRETORY, ANTIULCER STERLING DRUG INC. (US) 1979-02-20 US disclosed
US-RE29834-E PREPARED FROM 4-SULFONYL-1,8-NAPHTHOLACTAMS BAYER AKTIENGESELLSCHAFT (DE) 1978-11-14 US disclosed
US-4098797-A ANTISECRETORY, ANTIULCER AGENTS STERLING DRUG INC. (US) 1978-07-04 US disclosed
US-4016174-A USED IN PRESSURE SENSITIVE RECORD MATERIALS AND MANIFOLD MARKING SYSTEMS NCR CORPORATION (US) 1977-04-05 US disclosed
US-4008250-A ANTISECRETORY, ANTIULCER STERLING DRUG INC. (US) 1977-02-15 US disclosed
US-3959310-A BENZINDOLE BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746098-B2 Proteasome activity enhancing compounds PSMG3, PSMC1, PSMB11 MAPT 1252/4885ALDH1A1 3630/4885KDM4E 1032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.