Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 7/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450852 | 0.86 | CYP1A1 (0.41) | CYP1A1CYP1A2CYP1B1PTGS2PTGS1 | |
| SCHEMBL6448352 | 0.85 | CYP1A1 (0.45) | CYP1A1CYP1A2CYP1B1PTGS2PTGS1 | |
| SCHEMBL6453084 | 0.81 | NFE2L2 (0.60) | CYP1A1CYP1A2CYP1B1PTGS2PTGS1 | |
| SCHEMBL6449543 | 0.81 | NFE2L2 (0.54) | CYP1A1CYP1A2CYP1B1PTGS2PTGS1 | |
| SCHEMBL6459893 | 0.80 | CYP1A2 (0.45) | CYP1A1CYP1A2CYP1B1PTGS2PTGS1 | |
| SCHEMBL6448424 | 0.80 | TUBB1 (0.41) | CYP1A1CYP1A2CYP1B1PTGS2PTGS1 | |
| SCHEMBL917832 | 0.80 | TUBB1 (0.41) | CYP1A1CYP1A2CYP1B1PTGS2PTGS1 | |
| SCHEMBL6450699 | 0.79 | TUBB4A (0.62) | CYP1A1CYP1A2CYP1B1PTGS2PTGS1 | |
| SCHEMBL6453166 | 0.78 | CYP1A2 (0.58) | CYP1A1CYP1A2CYP1B1PTGS2PTGS1 | |
| SCHEMBL6450693 | 0.76 | PTGS2 (0.37) | CYP1A1CYP1A2CYP1B1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554236-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | Welichem Biotech Inc. (CA) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004031117-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | WELICHEM BIOTECH INC. (CA) | 2004-04-15 | — | — | WO | disclosed |