Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACR | P10323 | 2/20 | 0.44 |
| ▸ | DDX3X | O00571 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445843 | 0.81 | MAPT (0.52) | KMT2AHPGDMEN1POLBMAPT | |
| SCHEMBL6447209 | 0.80 | MAPT (0.44) | DDX3XKMT2AHPGDMEN1POLB | |
| SCHEMBL6453685 | 0.80 | MAPT (0.54) | KMT2AMEN1POLBKDM4EMAPT | |
| SCHEMBL6444242 | 0.79 | RAB9A (0.52) | KMT2AHPGDMEN1POLBKDM4E | |
| SCHEMBL6322386 | 0.79 | TRPV1 (0.53) | KMT2AHPGDMEN1POLBMAPT | |
| SCHEMBL6447202 | 0.78 | KMT2A (0.46) | KMT2AMEN1POLBKDM4EMAPT | |
| SCHEMBL6449238 | 0.78 | CSNK2A2 (0.52) | KMT2AMEN1POLBKDM4EMAPT | |
| SCHEMBL6445978 | 0.77 | SNCA (0.47) | KMT2AMEN1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL6447057 | 0.77 | KMT2A (0.52) | KMT2AHPGDMEN1POLBKDM4E | |
| SCHEMBL6325807 | 0.77 | TRPV1 (0.51) | KMT2AHPGDMEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143384-A1 | Amide thiadiazole inhibitors of plasminogen activator inhibitor-1 | BRISTOL-MYERS SQUIBB COMPANY | 2005-06-30 | — | — | US | claimed |
| WO-2023099719-A1 | EXPANDABLE PROTECTIVE COATING | H. K. WENTWORTH LIMITED (GB) | 2023-06-08 | — | — | WO | disclosed |
| EP-1606373-A1 | FABRIC CARE COMPOSITIONS COMPRISING CATIONIC STARCH | THE PROCTER & GAMBLE COMPANY (US) | 2005-12-21 | — | — | EP | disclosed |
| US-20050143384-A1 | Amide thiadiazole inhibitors of plasminogen activator inhibitor-1 | BRISTOL-MYERS SQUIBB COMPANY | 2005-06-30 | — | — | US | disclosed |
| WO-2004087854-A1 | FABRIC CARE COMPOSITIONS COMPRISING CATIONIC STARCH | THE PROCTER & GAMBLE COMPANY (US) | 2004-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143384-A1 | Amide thiadiazole inhibitors of plasminogen activator inhibitor-1 | SERPINE1, SERPINC1, SERPINB1 | ACR 2444/4885DDX3X 4246/4885KMT2A 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.