Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5962184 | 1.00 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL10508040 | 0.88 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL17965951 | 0.84 | MEN1 (0.47) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL9013326 | 0.84 | MEN1 (0.47) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL17965949 | 0.84 | MEN1 (0.47) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL10662711 | 0.83 | CCR6 (0.43) | ALDH1A1CCR6PAX8CTSBABCB1 | |
| SCHEMBL2736195 | 0.81 | ATM (0.43) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL9554875 | 0.80 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL7720033 | 0.77 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL8583695 | 0.76 | SLC15A1 (0.45) | ALDH1A1CCR6PAX8CTSBABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839798-B1 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LAB (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-0839798-A2 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5670675-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |