Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362550 | 0.86 | LMNA (0.49) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL2059549 | 0.83 | CTRB1 (0.49) | ALDH1A1L3MBTL1LMNACTRB1ABCB1 | |
| SCHEMBL7438541 | 0.83 | CTRB1 (0.49) | ALDH1A1L3MBTL1LMNACTRB1ABCB1 | |
| SCHEMBL7363077 | 0.82 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL10333560 | 0.82 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| Hydrochloric Acid SCHEMBL28475258 | 0.82 | CTRB1 (0.48) | ALDH1A1L3MBTL1LMNACTRB1KMT2A | |
| SCHEMBL8764792 | 0.81 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL7275088 | 0.81 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL8764783 | 0.81 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL7441915 | 0.81 | HSD17B10 (0.50) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |