Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710727 | 0.79 | L3MBTL1 (0.46) | L3MBTL1CTNNB1ATMMTNR1AKDM4E | |
| SCHEMBL6709447 | 0.78 | CTNNB1 (0.43) | L3MBTL1CTNNB1MTNR1AMAPTTHRB | |
| SCHEMBL1284854 | 0.69 | CTNNB1 (0.54) | L3MBTL1CTNNB1MTNR1ATDP1MEN1 | |
| SCHEMBL6444804 | 0.69 | SMN1; SMN2 (0.48) | L3MBTL1CTNNB1ATMKDM4ETDP1 | |
| SCHEMBL6444654 | 0.69 | AOC3 (0.40) | L3MBTL1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL1902233 | 0.69 | ATM (0.50) | L3MBTL1CTNNB1ATMMTNR1AKDM4E | |
| SCHEMBL6018293 | 0.69 | ATM (0.50) | L3MBTL1CTNNB1ATMMTNR1AKDM4E | |
| SCHEMBL8900559 | 0.69 | MTNR1A (0.57) | L3MBTL1CTNNB1MTNR1AMAPTTDP1 | |
| SCHEMBL15750674 | 0.69 | CTNNB1 (0.49) | L3MBTL1CTNNB1ATMKDM4ECYP1A2 | |
| SCHEMBL6447034 | 0.68 | AOC3 (0.42) | L3MBTL1KDM4ECYP1A2CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130941-A1 | Methods of treating alzheimer's disease | PHARMACIA & UPJOHN COMPANY LLC | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130941-A1 | Methods of treating alzheimer's disease | BACE1, PSEN1, BACE2 | L3MBTL1 2093/4885CTNNB1 1728/4885ATM 3339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.