Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | NLN | Q9BYT8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448997 | 0.78 | L3MBTL1 (0.45) | CTNNB1MMP9CYP1A2CYP2C19MTNR1A | |
| SCHEMBL7302653 | 0.75 | HTR1B (0.43) | CTNNB1MMP9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9666926 | 0.72 | CYP1A2 (0.47) | CTNNB1MMP9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7294849 | 0.71 | CTNNB1 (0.44) | CTNNB1MMP9METAP2CYP1A2CYP2D6 | |
| SCHEMBL7330802 | 0.70 | HTR1B (0.47) | CTNNB1MMP9METAP2CYP1A2CYP2D6 | |
| SCHEMBL6444409 | 0.69 | CTNNB1 (0.54) | CTNNB1MMP9CYP1A2MTNR1AL3MBTL1 | |
| SCHEMBL1284854 | 0.69 | CTNNB1 (0.54) | CTNNB1MMP9MTNR1AL3MBTL1TDP1 | |
| SCHEMBL6445346 | 0.69 | UTS2R (0.42) | UTS2RCYP1A2CYP2C19 | |
| SCHEMBL6442868 | 0.69 | MMP9 (0.45) | MMP9MTNR1A | |
| SCHEMBL8900559 | 0.69 | MTNR1A (0.57) | CTNNB1MTNR1AL3MBTL1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |