Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 7/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5671112 | 0.83 | CYP2A6 (0.38) | BRD4TDP1CYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL4802146 | 0.80 | KDM4E (0.44) | TDP1CYP2A6CYP1A2ALDH1A1NQO2 | |
| SCHEMBL1776822 | 0.78 | CYP1A2 (0.38) | BRD4TDP1CYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL1717201 | 0.78 | BRD4 (0.37) | BRD4TDP1CYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL10822441 | 0.78 | BRD4 (0.37) | BRD4TDP1CYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL10822591 | 0.78 | MAPT (0.35) | TDP1CYP2A6CYP1A2ALDH1A1TSHR | |
| SCHEMBL3269198 | 0.78 | ACHE (0.34) | TDP1CYP2A6CYP1A2ACHEMBNL1 | |
| SCHEMBL10822588 | 0.78 | BRD4 (0.37) | BRD4TDP1CYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL76620 | 0.78 | IDO1 (0.34) | TDP1CYP2A6ALDH1A1TSHRHPGD | |
| SCHEMBL11008069 | 0.78 | CYP2A6 (0.32) | TDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2194 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884405-B | Lubricating oil composition | 出光兴产株式会社 | 2023-01-17 | — | — | CN | claimed |
| US-20220220101-A1 | COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION | OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) | 2022-07-14 | — | — | US | claimed |
| CN-110168061-B | Lubricating oil composition | 出光兴产株式会社 | 2022-05-17 | — | — | CN | claimed |
| EP-3625223-B1 | PYRIMIDINE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-08-11 | — | — | EP | claimed |
| US-20200108068-A1 | PYRIMIDINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2020-04-09 | — | — | US | claimed |
| EP-3625223-A1 | PYRIMIDINE DERIVATIVES | Idorsia Pharmaceuticals Ltd (CH) | 2020-03-25 | — | — | EP | claimed |
| CN-110621667-A | Pyrimidine derivatives | 爱杜西亚药品有限公司 | 2019-12-27 | — | — | CN | claimed |
| WO-2018210992-A1 | PYRIMIDINE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2018-11-22 | — | — | WO | claimed |
| CN-106892945-A | A kind of N-heterocyclic carbine-palladium complex, its preparation method and application | 温州大学 | 2017-06-27 | — | — | CN | claimed |
| CN-104447324-A | Arylalkyl methacrylate as well as preparation method and application thereof | DALIAN ORIENT CREATIVE TECHNOLOGY CO LTD | 2015-03-25 | — | — | CN | claimed |
| US-5130603-A | A stilbene, bluish purple to green | IDEMITSU KOSAN CO., LTD. (JP) | 1992-07-14 | — | — | US | claimed |
| US-5034364-A | Silylchromium compounds and polymers as polymerization catalysts | MOBIL OIL CORPORATION (US) | 1991-07-23 | — | — | US | claimed |
| US-5010082-A | Fungicides, microbiocides | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | claimed |
| EP-0362135-A2 | Parasiticide | CIBA-GEIGY AG (CH) | 1990-04-04 | — | — | EP | claimed |
| US-RE31300-E | Process for preparing alkyl- or arylphosphonothioic dihalides | STAUFFER CHEMICAL COMPANY (US) | 1983-07-05 | — | — | US | claimed |
| US-4130583-A | AUTOGENOUS PRESSURE | STAUFFER CHEMICAL COMPANY (US) | 1978-12-19 | — | — | US | claimed |
| US-4052463-A | PROCESS FOR PREPARING TERTIARY PHOSPHINE SULFIDES AND OXIDES | STAUFFER CHEMICAL COMPANY (US) | 1977-10-04 | — | — | US | claimed |
| US-4000190-A | FROM DIALKYL OR DIARYL DISULFIDES, PHOSPHORUS, AND PHOSPHORUS TRIHALIDE | STAUFFER CHEMICAL COMPANY (US) | 1976-12-28 | — | — | US | claimed |
| US-3968156-A | Process for preparing alkyl-or arylphosphonothioic dihalides | STAUFFER CHEMICAL COMPANY (US) | 1976-07-06 | — | — | US | claimed |
| US-3962323-A | PHOSPHORUS TRIHALIDE | STAUFFER CHEMICAL COMPANY (US) | 1976-06-08 | — | — | US | claimed |