SCHEMBL76620

SCHEMBL76620

Cc1[c]c2ccccc2cc1N

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.34
CYP3A4 P08684 6/20 0.33
TDP1 Q9NUW8 3/20 0.33
POLB P06746 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NCF1 P14598 1/20 0.33
PDPK1 O15530 1/20 0.33
ALDH1A1 P00352 3/20 0.32
HSD17B10 Q99714 3/20 0.32
TSHR P16473 2/20 0.32
HPGD P15428 1/20 0.32
KEAP1 Q14145 1/20 0.32
CYP2A6 P11509 1/20 0.32
HPRT1 P00492 1/20 0.31
ALOX15 P16050 2/20 0.31
CASP1 P29466 2/20 0.31
CASP7 P55210 2/20 0.31
HBB P68871 1/20 0.31
HIF1A Q16665 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL731428 0.78 IDO1 (0.36) IDO1CYP3A4TDP1POLBSMN1; SMN2
SCHEMBL64492 0.78 BRD4 (0.39) TDP1ALDH1A1HSD17B10TSHRHPGD
SCHEMBL4802146 0.77 KDM4E (0.44) TDP1POLBALDH1A1HSD17B10HPGD
SCHEMBL11764397 0.75 IDO1 (0.38) IDO1CYP3A4TDP1POLBSMN1; SMN2
SCHEMBL10822441 0.75 BRD4 (0.37) CYP3A4TDP1PDPK1ALDH1A1HSD17B10
SCHEMBL3269198 0.75 ACHE (0.34) TDP1CYP2A6HPRT1
SCHEMBL11008069 0.75 CYP2A6 (0.32) TDP1CYP2A6
SCHEMBL10822591 0.75 MAPT (0.35) TDP1ALDH1A1TSHRCYP2A6MAPT
SCHEMBL258295 0.72 MAPT (0.40) TDP1ALDH1A1CYP2A6MAPT
SCHEMBL2458782 0.72 TDP1 (0.33) TDP1ALDH1A1TSHRCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 621 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118339214-A Coating composition PPG工业俄亥俄公司 2024-07-12 CN disclosed
US-12018110-B2 Acrylic polyester resin and an aqueous coating composition containing the same PPG INDUSTRIES OHIO, INC. (US) 2024-06-25 US disclosed
EP-4382545-A2 AN ACRYLIC POLYESTER RESIN AND AN AQUEOUS COATING COMPOSITION CONTAINING THE SAME PPG Industries Ohio, Inc. (US) 2024-06-12 EP disclosed
CN-115678377-B Acrylic polyester resin and aqueous coating composition containing same PPG工业俄亥俄公司 2024-05-28 CN disclosed
EP-4372020-A2 AN ACRYLIC POLYESTER RESIN AND AN AQUEOUS COATING COMPOSITION CONTAINING THE SAME PPG Industries Ohio, Inc. (US) 2024-05-22 EP disclosed
US-20240158650-A1 A COATING COMPOSITION PPG COATINGS EUROPE B.V. (NL) 2024-05-16 US disclosed
US-11981764-B2 Acrylic polyester resin and an aqueous coating composition containing the same PPG INDUSTRIES OHIO, INC. (US) 2024-05-14 US disclosed
WO-2024074813-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT OWLSTONE MEDICAL LIMITED (GB) 2024-04-11 WO disclosed
EP-3800210-B1 AN ACRYLIC POLYESTER RESIN AND AN AQUEOUS COATING COMPOSITION CONTAINING THE SAME PPG IND OHIO INC (US) 2024-04-10 EP disclosed
EP-3800212-B1 AN ACRYLIC POLYESTER RESIN AND AN AQUEOUS COATING COMPOSITION CONTAINING THE SAME PPG IND OHIO INC (US) 2024-04-10 EP disclosed
EP-0813519-A1 SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1997-12-29 EP disclosed
EP-0804428-A1 BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1997-11-05 EP disclosed
WO-1997018205-A1 SUBSTITUTED SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1997-05-22 WO disclosed
WO-1997018190-A1 N-PROTECTED/N-SUBSTITUTED-BETA-AMINO HYDROXY SULFONATES G.D. SEARLE & CO. (US) 1997-05-22 WO disclosed
WO-1996028418-A1 SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1996-09-19 WO disclosed
WO-1996028465-A1 HETEROCYCLECARBONYL AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1996-09-19 WO disclosed
WO-1996028463-A1 AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1996-09-19 WO disclosed
WO-1996022287-A1 BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1996-07-25 WO disclosed
EP-0715618-A1 HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1996-06-12 EP disclosed
WO-1995006030-A1 HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1995-03-02 WO disclosed