Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847189 | 0.81 | NPC1 (0.58) | L3MBTL1SMN1; SMN2PKMRAB9AALDH1A1 | |
| SCHEMBL7822161 | 0.80 | L3MBTL1 (0.56) | L3MBTL1HPGDSMN1; SMN2MAPK8MAPK9 | |
| SCHEMBL13918020 | 0.80 | L3MBTL1 (0.52) | L3MBTL1HPGDSMN1; SMN2GSK3AGSK3B | |
| SCHEMBL5796829 | 0.80 | L3MBTL1 (0.52) | L3MBTL1HPGDSMN1; SMN2GSK3AGSK3B | |
| SCHEMBL5812520 | 0.80 | L3MBTL1 (0.52) | L3MBTL1GSK3AGSK3BMAPK8MAPK9 | |
| SCHEMBL9061909 | 0.80 | L3MBTL1 (0.52) | L3MBTL1CYP3A4HPGDGSK3AGSK3B | |
| SCHEMBL5616888 | 0.78 | L3MBTL1 (0.50) | L3MBTL1CYP3A4SMN1; SMN2GSK3AGSK3B | |
| SCHEMBL4358141 | 0.75 | L3MBTL1 (0.85) | L3MBTL1SMN1; SMN2PKMRAB9AKMT2A | |
| SCHEMBL8985073 | 0.73 | GSK3B (0.67) | L3MBTL1CYP3A4HPGDSMN1; SMN2PKM | |
| SCHEMBL13932146 | 0.73 | PDE4A (0.49) | L3MBTL1GSK3AGSK3BKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1510545-A2 | 1,3 substituted 6-aminouraciles to stabilize halogenated polymers | Wehner, Wolfgang, Dr. (DE) | 2005-03-02 | — | — | EP | disclosed |