1-Naphthol

1-Naphthol

SCHEMBL6449294

C=O.Oc1cccc2ccccc12.Oc1ccccc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.71
ESR1 P03372 2/20 0.48
ESR2 Q92731 2/20 0.48
HSD17B1 P14061 2/20 0.48
HSD17B2 P37059 2/20 0.48
NQO2 P16083 1/20 0.47
GLA P06280 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
NR4A1 P22736 1/20 0.45
NR4A2 P43354 1/20 0.45
NR4A3 Q92570 1/20 0.45
PTPN22 Q9Y2R2 1/20 0.43
GRIN2D O15399 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL29959385 0.94 CYP1A2 (0.81) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL28448239 0.94 CYP1A2 (0.81) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL28127258 0.94 CYP1A2 (0.81) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL94756 0.94 CYP1A2 (0.81) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL27693098 0.91 CYP1A2 (0.77) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL29400138 0.91 CYP1A2 (0.85) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL27894038 0.91 CYP1A2 (0.85) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL917962 0.91 CYP1A2 (0.85) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL27555143 0.89 CYP1A2 (0.81) CYP1A2ESR1ESR2HSD17B1HSD17B2
Biphenyl SCHEMBL28506877 0.88 CYP1A2 (0.71) CYP1A2ESR1ESR2HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113710725-A Crosslinkable networks from functionalized polyetherimides and thermoset polymers therefrom 高新特殊工程塑料全球技术有限公司 2021-11-26 CN disclosed
CN-106279704-B Polyphenyl ether modified phenol-benzaldehyde multifunctional epoxy resin and application 南亚塑胶工业股份有限公司 2020-10-27 CN disclosed
CN-1244610-C Cyanate ester based thermoset compositions GEN ELECTRIC (US) 2006-03-08 CN disclosed
EP-0921158-B1 Poly(phenylene ether) thermoset compositions GEN ELECTRIC (US) 2005-09-14 EP disclosed
EP-0945477-B1 Cyanate ester based thermoset compositions GEN ELECTRIC (US) 2004-09-22 EP disclosed
CN-1101420-C Poly (phenylene ether) thermoset compositions GEN ELECTRIC (US) 2003-02-12 CN disclosed
CN-1379800-A Cyanate ester based thermoset compositions GEN ELECTRIC (US) 2002-11-13 CN disclosed
US-6403229-B2 CURABLE COMPOSITIONS OF A CYANATE ESTER AND A CYANATE ESTER PREPOLYMER, A CYANATE ESTER-FREE ARYLOXYTRIAZINE, AND A CURING CATALYST USED IN CIRCUIT BOARDS, STRUCTURAL COMPOSITES, ENCAPSULATING RESINS, ETC... GENERAL ELECTRIC COMPANY 2002-06-11 US disclosed
EP-1208159-A1 CYANATE ESTER BASED THERMOSET COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2002-05-29 EP disclosed
US-20010016616-A1 Cyanate ester based thermoset compositions CERBERUS BUSINESS FINANCE, LLC, AS COLLATERAL AGENT (FIRST LIEN) 2001-08-23 US disclosed
US-6245841-B1 BLEND CONTAINING FLAME RETARDER AND CURING AGENT GENERAL ELECTRIC COMPANY 2001-06-12 US disclosed
US-6194495-B1 CURBLE COMPOSITION WITH ARYLOXYTRIAZINE GENERAL ELECTRIC COMPANY 2001-02-27 US disclosed
WO-2001009247-A1 CYANATE ESTER BASED THERMOSET COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2001-02-08 WO disclosed
US-6162876-A Cyanate ester based thermoset compositions GENERAL ELECTRIC COMPANY (US) 2000-12-19 US disclosed
EP-0945477-A1 Cyanate ester based thermoset compositions GENERAL ELECTRIC COMPANY (US) 1999-09-29 EP disclosed
CN-1229817-A Cyanate ester based thermoset compositions GEN ELECTRIC (US) 1999-09-29 CN disclosed
EP-0921158-A2 Poly(phenylene ether) thermoset compositions GENERAL ELECTRIC COMPANY (US) 1999-06-09 EP disclosed
CN-1218073-A Poly (phenylene ether) thermoset compositions GEN ELECTRIC (US) 1999-06-02 CN disclosed
US-4588671-A Photo and electron resist with donor-acceptor complex and light sensitive compound INSTITUT KHIMII AKADEMII NAUK SSSR (SU) 1986-05-13 US disclosed
US-4560384-A Process for tanning hides Guidi, Loris (IT) 1985-12-24 US disclosed