1-Naphthol

1-Naphthol

SCHEMBL917962

C=O.Oc1cccc2ccccc12

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.85
PTPN22 Q9Y2R2 1/20 0.50
IDO1 P14902 1/20 0.50
PLAU P00749 1/20 0.48
KDM4E B2RXH2 1/20 0.48
MAPKAPK2 P49137 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
NQO2 P16083 1/20 0.48
HSD17B10 Q99714 3/20 0.48
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
APP P05067 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
CASP1 P29466 1/20 0.48
SNCA P37840 1/20 0.48
RECQL P46063 1/20 0.48
POLB P06746 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL29400138 1.00 CYP1A2 (0.85) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL11335707 0.92 CYP1A2 (0.90) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL29767730 0.92 CYP1A2 (1.00) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL3416 0.92 CYP1A2 (1.00) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL10486461 0.92 CYP1A2 (1.00) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL273260 0.92 CYP1A2 (1.00) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL6449294 0.91 CYP1A2 (0.71) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL3924043 0.90 CYP1A2 (0.94) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL9850309 0.90 CYP1A2 (0.94) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL11295882 0.90 CYP1A2 (0.94) CYP1A2PTPN22IDO1PLAUKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118731194-A Detection method of alkyl diamine 四川科伦药物研究院有限公司 2024-10-01 CN claimed
CN-115368221-B Small molecule carrier, preparation method thereof and application thereof in polypeptide synthesis 成都圣诺生物科技股份有限公司 2023-05-23 CN claimed
CN-115191433-A Application of functional additive in cockroach killing composition, cockroach killing composition and application of cockroach killing composition 中国人民解放军海军特色医学中心 2022-10-18 CN claimed
CN-113880998-A Anti-mud polycarboxylate superplasticizer and preparation method thereof 重庆三圣实业股份有限公司 2022-01-04 CN claimed
CN-107827825-B Synthesis and application of benzimidazolyl supramolecular gelator based on hydroxynaphthalene formaldehyde functionalization 西北师范大学 2020-01-21 CN claimed
CN-109476830-A Hardener composition and relevant manufacturing process, uncured and cured composition epoxy resin and product 沙特基础工业全球技术有限公司 2019-03-15 CN claimed
CN-108753274-A The preparation method of crosslinked acrylic resin polymer wrapped pigment yellow fluorescent nano particles 华东理工大学 2018-11-06 CN claimed
CN-108290386-A It forms the method for cured epoxy material, the cured epoxy material formed by it, useful phenylene ether oligomer-anhydride reaction product and combine the composite material core of cured epoxy material in the method 沙特基础工业全球技术有限公司 2018-07-17 CN claimed
CN-104902900-A Treatment of viral and infectious diseases using an inhibitor of cbp/catenin PRISMA PHARMACY CORP 2015-09-09 CN claimed
CN-102911191-B Preparation method for ethanol 2-hydroxyl naphthaldehyde thiosemicarbazone o-phenanthroline metal complex UNIV SHANGQIU NORMAL 2015-05-06 CN claimed
CN-1194999-C Epoxy resin containing naphthalein and alicyclic hydrocarbon structure and its preparation method GUANG ZHOU INST OF CHEMISTRY C (CN) 2005-03-30 CN claimed
CN-1475513-A Epoxy resin containing naphthalein and alicyclic hydrocarbon structure and its preparation method 中国科学院广州化学研究所 2004-02-18 CN claimed
CN-1439027-A Process for the manufacture of hydroxy ester derivative intermediates and epoxy resins prepared therefrom DOW GLOBAL TECHNOLOGIES COMPAN (US) 2003-08-27 CN claimed
CN-1067735-C Process for the application of dye fixing agents to polyamide fiber utilizing controlled fixing agent addition DU PONT (US) 2001-06-27 CN claimed
CN-1295637-A Selective retention of filling components and improved control of sheet properties by enhancing additive pretreatment NALCO CHEMICAL CO (US) 2001-05-16 CN claimed
CN-1124987-A Process for the application of dye fixing agents to polyamide fiber utilizing controlled fixing agent addition DU PONT (US) 1996-06-19 CN claimed
US-4877538-A Sulfomethylated stain blocking agents CROMPTON & KNOWLES CORPORATION (US) 1989-10-31 US claimed
US-4865885-A Food color stain blocking fiber agents CROMPTON & KNOWLES CORPORATION (US) 1989-09-12 US claimed
US-4126470-A WATER-REPELLENT MATERIAL; POLYALKYLENE GLYCOL; SULFONATED PHENOL OR MELAMINE FORMALDEHYDE CONDENSATE OR SUGAR ACID AND AMINO ACID SUDDEUTSCHE KALKSTICKSTOFF-WERKE AKTIENGESELLSCHAFT (DE) 1978-11-21 US claimed
US-4070236-A Paper manufacture with improved retention agents SANDOZ LTD. (CH) 1978-01-24 US claimed