1-Naphthol

1-Naphthol

SCHEMBL29959385

Oc1cccc2ccccc12.Oc1ccccc1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.81
ESR1 P03372 2/20 0.53
ESR2 Q92731 2/20 0.53
HSD17B1 P14061 2/20 0.53
HSD17B2 P37059 2/20 0.53
TDP1 Q9NUW8 3/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
GLA P06280 1/20 0.52
CA3 P07451 1/20 0.52
CA4 P22748 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
NQO2 P16083 1/20 0.52
PTPN22 Q9Y2R2 1/20 0.48
IDO1 P14902 1/20 0.48
PLAU P00749 1/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPKAPK2 P49137 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL94756 1.00 CYP1A2 (0.81) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL28448239 1.00 CYP1A2 (0.81) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL6449294 0.94 CYP1A2 (0.71) CYP1A2ESR1ESR2HSD17B1HSD17B2
Biphenyl SCHEMBL28506877 0.94 CYP1A2 (0.71) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL3416 0.90 CYP1A2 (1.00) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL29767730 0.90 CYP1A2 (1.00) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL10486461 0.90 CYP1A2 (1.00) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL273260 0.90 CYP1A2 (1.00) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL11250007 0.88 CYP1A2 (0.77) CYP1A2ESR1ESR2HSD17B1HSD17B2
Phenol SCHEMBL8526528 0.87 IDO1 (0.63) CYP1A2ESR1ESR2HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320180-A1 HYDROXYL GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, CURED PRODUCT, AND LAYERED PRODUCT DIC CORPORATION (JP) 2025-10-16 US disclosed
US-20250277081-A1 GLYCIDYL ETHER GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, CURED OBJECT, AND LAMINATE DIC CORPORATION (JP) 2025-09-04 US disclosed
US-20250277080-A1 PHENOLIC HYDROXY GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, CURED PRODUCT, AND LAMINATE DIC CORPORATION (JP) 2025-09-04 US disclosed
US-20250223396-A1 GLYCIDYL ETHER GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, CURED PRODUCT, AND LAMINATE DIC CORPORATION (JP) 2025-07-10 US disclosed
US-20250179237-A1 GLYCIDYL ETHER GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, CURED PRODUCT, AND LAMINATE DIC CORPORATION (JP) 2025-06-05 US disclosed
EP-4527834-A1 GLYCIDYL ETHER GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, CURED OBJECT, AND LAMINATE DIC Corporation (JP) 2025-03-26 EP disclosed
EP-4527839-A1 PHENOLIC HYDROXY GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, CURED PRODUCT, AND LAMINATE DIC Corporation (JP) 2025-03-26 EP disclosed
EP-4527832-A1 HYDROXYL GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, CURED PRODUCT, AND LAYERED PRODUCT DIC Corporation (JP) 2025-03-26 EP disclosed
EP-4527870-A1 GLYCIDYL ETHER GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, CURED PRODUCT, AND LAMINATE DIC Corporation (JP) 2025-03-26 EP disclosed
EP-4527869-A1 GLYCIDYL ETHER GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, CURED PRODUCT, AND LAMINATE DIC Corporation (JP) 2025-03-26 EP disclosed
WO-2023171514-A1 LAMINATE AND PACKAGING MATERIAL DIC株式会社 2023-09-14 WO disclosed
WO-2022202781-A1 THERMOSETTING RESIN COMPOSITION, HIGH FREQUENCY DEVICE, DIELECTRIC SUBSTRATE, AND MICROSTRIP ANTENNA 住友ベークライト株式会社 2022-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250320180-A1 HYDROXYL GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, CURED PRODUCT, AND LAYERED PRODUCT RAD51, SEM1, GFER CYP1A2 865/4885ESR1 1003/4885ESR2 996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.