1-Naphthol

1-Naphthol

SCHEMBL28448239

Oc1cccc2ccccc12.Oc1ccccc1.Oc1ccccc1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.81
ESR1 P03372 2/20 0.53
ESR2 Q92731 2/20 0.53
HSD17B1 P14061 2/20 0.53
HSD17B2 P37059 2/20 0.53
TDP1 Q9NUW8 3/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
GLA P06280 1/20 0.52
CA3 P07451 1/20 0.52
CA4 P22748 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
NQO2 P16083 1/20 0.52
PTPN22 Q9Y2R2 1/20 0.48
IDO1 P14902 1/20 0.48
PLAU P00749 1/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPKAPK2 P49137 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL94756 1.00 CYP1A2 (0.81) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL29959385 1.00 CYP1A2 (0.81) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL6449294 0.94 CYP1A2 (0.71) CYP1A2ESR1ESR2HSD17B1HSD17B2
Biphenyl SCHEMBL28506877 0.94 CYP1A2 (0.71) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL3416 0.90 CYP1A2 (1.00) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL29767730 0.90 CYP1A2 (1.00) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL10486461 0.90 CYP1A2 (1.00) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL273260 0.90 CYP1A2 (1.00) CYP1A2ESR1ESR2HSD17B1HSD17B2
1-Naphthol SCHEMBL11250007 0.88 CYP1A2 (0.77) CYP1A2ESR1ESR2HSD17B1HSD17B2
Phenol SCHEMBL8526528 0.87 IDO1 (0.63) CYP1A2ESR1ESR2HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111527152-B Thermosetting composition, thermosetting resin modifier, cured product thereof, semiconductor sealing material, prepreg, circuit board, and build-up film DIC株式会社 2022-04-29 CN disclosed
CN-111527152-A Thermosetting composition, thermosetting resin modifier, cured product thereof, semiconductor sealing material, prepreg, circuit board, and build-up film DIC株式会社 2020-08-11 CN disclosed