Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1651816 | 0.86 | ACP3 (0.41) | ACP3KMT2AALDH1A1POLB | |
| SCHEMBL6448011 | 0.73 | ALDH1A1 (0.44) | TAS1R3TAS1R1KMT2AALDH1A1POLB | |
| SCHEMBL10928799 | 0.72 | ACP3 (0.66) | ACP3FDPSPOLB | |
| SCHEMBL15418608 | 0.71 | ALDH1A1 (0.46) | KMT2AALDH1A1POLB | |
| SCHEMBL27464136 | 0.70 | CYP2C9 (0.46) | — | |
| SCHEMBL12056790 | 0.69 | ALDH1A1 (0.44) | KMT2AALDH1A1POLB | |
| SCHEMBL10773562 | 0.69 | ALDH1A1 (0.45) | ACP3ALDH1A1 | |
| SCHEMBL23002322 | 0.68 | ALDH1A1 (0.38) | TAS1R3TAS1R1KMT2AMEN1ALDH1A1 | |
| SCHEMBL20362018 | 0.68 | ADRB1 (0.43) | TAS1R3TAS1R1KMT2AMEN1POLB | |
| SCHEMBL5798610 | 0.67 | PGK1 (0.55) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554236-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | Welichem Biotech Inc. (CA) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004031117-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | WELICHEM BIOTECH INC. (CA) | 2004-04-15 | — | — | WO | disclosed |