Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29627704 | 1.00 | HSP90AA1 (0.42) | HSP90AA1KDM4ETP53TDP1MAPK14 | |
| SCHEMBL5989213 | 0.87 | HSP90AA1 (0.44) | HSP90AA1MAPK14MAPK9MAPK11MAPK13 | |
| SCHEMBL25295479 | 0.82 | TP53 (0.48) | HSP90AA1TP53MAPK14MAPK9MAPK11 | |
| SCHEMBL29430257 | 0.82 | TP53 (0.48) | HSP90AA1TP53MAPK14MAPK9MAPK11 | |
| SCHEMBL2814353 | 0.81 | HSP90AA1 (0.52) | HSP90AA1KDM4EMAPK14MAPK9MAPK11 | |
| SCHEMBL30595872 | 0.81 | HSP90AA1 (0.52) | HSP90AA1KDM4EMAPK14MAPK9MAPK11 | |
| SCHEMBL5788253 | 0.79 | GRM5 (0.39) | HSP90AA1MAPK14MAPK9MAPK11MAPK13 | |
| SCHEMBL21315705 | 0.78 | KDM4E (0.55) | HSP90AA1KDM4ETP53TDP1GRM5 | |
| SCHEMBL13910999 | 0.78 | HSP90AA1 (0.50) | HSP90AA1MAPK14MAPK9MAPK11MAPK13 | |
| SCHEMBL29394083 | 0.78 | KDM4E (0.67) | HSP90AA1KDM4ETP53TDP1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892617-B1 | FLUORINATED PYRIMIDINE COMPOUND AND PRODUCTION METHOD THEREFOR | UNIMATEC CO LTD (JP) | 2025-04-30 | — | — | EP | disclosed |
| US-12043615-B2 | Fluorine-containing pyrimidine compound and method for manufacturing the same | UNIMATEC CO., LTD. (JP) | 2024-07-23 | — | — | US | disclosed |
| CN-112739689-B | Fluorine-containing pyrimidine compound and method for producing same | 优迈特株式会社 | 2022-06-03 | — | — | CN | disclosed |
| US-20210403455-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND METHOD FOR MANUFACTURING THE SAME | UNIMATEC CO., LTD. (JP) | 2021-12-30 | — | — | US | disclosed |
| EP-3892617-A1 | FLUORINATED PYRIMIDINE COMPOUND AND PRODUCTION METHOD THEREFOR | Unimatec Co., Ltd. (JP) | 2021-10-13 | — | — | EP | disclosed |
| CN-112739689-A | Fluorine-containing pyrimidine compound and method for producing same | 优迈特株式会社 | 2021-04-30 | — | — | CN | disclosed |
| WO-2020116296-A1 | FLUORINATED PYRIMIDINE COMPOUND AND PRODUCTION METHOD THEREFOR | ユニマテック株式会社 | 2020-06-11 | — | — | WO | disclosed |
| EP-3466932-A1 | PRODUCTION METHOD FOR BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Kobelco Eco-Solutions Co., Ltd (JP) | 2019-04-10 | — | — | EP | disclosed |
| CN-101535314-A | Substituted 8-piperidinyl-2-pyridinyl-pyrimido [1, 2-a ] pyrimidin-6-one and 8-piperidinyl-2-pyrimidinyl-pyrimido [1, 2-a ] pyrimidin-6-one derivatives | SANOFI AVENTIS MITSUBISHI TANA (FR) | 2009-09-16 | — | — | CN | disclosed |
| US-6949644-B2 | Methods for the synthesis of substituted purines | IRM LLC (BM) | 2005-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043615-B2 | Fluorine-containing pyrimidine compound and method for manufacturing the same | CNOT1, NUDT1, XRN2 | HSP90AA1 2096/4885KDM4E 4521/4885TP53 2258/4885 |
| US-20210403455-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND METHOD FOR MANUFACTURING THE SAME | CNOT1, NUDT1, XRN2 | HSP90AA1 2096/4885KDM4E 4521/4885TP53 2258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.