SCHEMBL644964

SCHEMBL644964

CCCP(=O)(Oc1ccc(C(=O)c2ccccc2)cc1)Oc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.54
ALDH1A1 P00352 4/20 0.49
HPGD P15428 2/20 0.49
GAA P10253 2/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
LMNA P02545 3/20 0.47
HTT P42858 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MAPT P10636 2/20 0.47
RAB9A P51151 2/20 0.47
MAPK1 P28482 1/20 0.47
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
PPARA Q07869 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12198436 0.83 ELANE (0.53) ELANEALDH1A1HPGDGAAL3MBTL1
SCHEMBL4454035 0.83 L3MBTL1 (0.53) L3MBTL1LMNAHTTMEN1KMT2A
SCHEMBL16239049 0.79 KLK8 (0.55) ELANEALDH1A1GAAL3MBTL1HTT
SCHEMBL15326120 0.78 ELANE (0.59) ELANEALDH1A1HPGDGAAL3MBTL1
SCHEMBL12198434 0.78 ELANE (0.58) ELANEALDH1A1GAAL3MBTL1RAB9A
SCHEMBL16809075 0.77 ELANE (0.46) ELANEALDH1A1HPGDGAAL3MBTL1
SCHEMBL10014792 0.76 LTA4H (0.43) LMNASMN1; SMN2MAPK1MEN1KMT2A
SCHEMBL28324296 0.76 SRC (0.67) ELANEALDH1A1GAARAB9AMEN1
SCHEMBL2553373 0.76 ELANE (0.56) ELANEALDH1A1GAAL3MBTL1RAB9A
SCHEMBL20806036 0.76 GAA (0.45) ELANEALDH1A1GAAL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090163638-A1 Dispersion of deagglomerated barium sulphate in halogenated solvents, ethers or esters SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2009-06-25 US claimed
US-20090020042-A1 Use of Nanoparticles for the Preparation of Water-Based Dispersion Adhesives SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2009-01-22 US claimed
US-20080312362-A1 Method of Generating a Dispersion of Deagglomerated Barium Sulphate in Plastics or Plastics Precursors SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2008-12-18 US claimed
EP-1984470-A1 USE OF NANOPARTICLES FOR THE PREPARATION OF WATER-BASED DISPERSION ADHESIVES Solvay Infra Bad Hönningen GmbH (DE) 2008-10-29 EP claimed
US-20080190325-A1 Modified Nanoparticles SOLVAY INFRA BAD HOENINGEN GMBH (DE) 2008-08-14 US claimed
EP-1891166-A1 METHOD OF GENERATING A DISPERSION OF DEAGGLOMERATED BARIUM SULPHATE IN PLASTICS OR PLASTICS PRECURSORS Solvay Infra Bad Hönningen GmbH (DE) 2008-02-27 EP claimed
EP-1891165-A1 DISPERSION OF DEAGGLOMERATED BARIUM SULPHATE IN HALOGENATED SOLVENTS, ETHERS OR ESTERS Solvay Infra Bad Hönningen GmbH (DE) 2008-02-27 EP claimed
WO-2007090813-A1 USE OF NANOPARTICLES FOR THE PREPARATION OF WATER-BASED DISPERSION ADHESIVES SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2007-08-16 WO claimed
WO-2006131500-A1 METHOD OF GENERATING A DISPERSION OF DEAGGLOMERATED BARIUM SULPHATE IN PLASTICS OR PLASTICS PRECURSORS SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2006-12-14 WO claimed
WO-2006131492-A1 DISPERSION OF DEAGGLOMERATED BARIUM SULPHATE IN HALOGENATED SOLVENTS, ETHERS OR ESTERS SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2006-12-14 WO claimed
US-8119716-B2 Method of generating a dispersion of deagglomerated barium sulphate in plastics or plastics precursors SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2012-02-21 US disclosed
US-20090163638-A1 Dispersion of deagglomerated barium sulphate in halogenated solvents, ethers or esters SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2009-06-25 US disclosed
CN-101379157-A Use of nanoparticles for producing water-based dispersion adhesives SOLVAY INFRA BAD HOENNINGEN GM (DE) 2009-03-04 CN disclosed
US-20090020042-A1 Use of Nanoparticles for the Preparation of Water-Based Dispersion Adhesives SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2009-01-22 US disclosed
US-20080312362-A1 Method of Generating a Dispersion of Deagglomerated Barium Sulphate in Plastics or Plastics Precursors SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2008-12-18 US disclosed
EP-1891168-A1 MODIFIED NANOPARTICLES Solvay Infra Bad Hönningen GmbH (DE) 2008-02-27 EP disclosed
WO-2007090813-A1 USE OF NANOPARTICLES FOR THE PREPARATION OF WATER-BASED DISPERSION ADHESIVES SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2007-08-16 WO disclosed
WO-2006131500-A1 METHOD OF GENERATING A DISPERSION OF DEAGGLOMERATED BARIUM SULPHATE IN PLASTICS OR PLASTICS PRECURSORS SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2006-12-14 WO disclosed
WO-2006131497-A1 MODIFIED NANOPARTICLES SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2006-12-14 WO disclosed
WO-2006131492-A1 DISPERSION OF DEAGGLOMERATED BARIUM SULPHATE IN HALOGENATED SOLVENTS, ETHERS OR ESTERS SOLVAY INFRA BAD HOENNINGEN GMBH (DE) 2006-12-14 WO disclosed