SCHEMBL2553373

SCHEMBL2553373

O=C(c1ccccc1)c1ccc(OP(=O)(O)Oc2ccc(C(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 8/20 0.56
ALDH1A1 P00352 1/20 0.54
SRD5A2 P31213 2/20 0.52
STS P08842 1/20 0.51
GAA P10253 1/20 0.51
SRC P12931 1/20 0.50
POLB P06746 2/20 0.49
PPARA Q07869 1/20 0.47
MEN1 O00255 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
KMT2A Q03164 1/20 0.47
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25184218 0.90 ELANE (0.50) ELANEALDH1A1SRD5A2STSGAA
SCHEMBL28324296 0.89 SRC (0.67) ELANEALDH1A1SRD5A2STSGAA
SCHEMBL14672258 0.88 ELANE (0.49) ELANEALDH1A1SRD5A2STSGAA
SCHEMBL20508785 0.88 ELANE (0.49) ELANEALDH1A1SRD5A2STSGAA
SCHEMBL20508796 0.88 ELANE (0.49) ELANEALDH1A1SRD5A2STSGAA
SCHEMBL19261213 0.87 SRD5A2 (0.51) ELANEALDH1A1SRD5A2STSGAA
SCHEMBL14672257 0.87 SRC (0.64) ELANEALDH1A1SRD5A2STSGAA
SCHEMBL12198434 0.86 ELANE (0.58) ELANEALDH1A1SRD5A2STSGAA
SCHEMBL10045721 0.84 ELANE (0.51) ELANEALDH1A1SRD5A2STSGAA
SCHEMBL15326120 0.83 ELANE (0.59) ELANEALDH1A1SRD5A2STSGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098225-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES SURMODICS INC (US) 2026-04-09 US claimed
US-12441951-B2 Polyacrylic acid containing lubricious coatings for medical devices with enhanced properties SURMODICS, INC. (US) 2025-10-14 US claimed
EP-4615530-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES SurModics, Inc. (US) 2025-09-17 EP claimed
EP-4489804-A1 THROMBORESISTANT COATINGS, COATED DEVICES, AND METHODS Surmodics Coatings, LLC (US) 2025-01-15 EP claimed
US-20240240098-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES BANK OF MONTREAL, AS COLLATERAL AGENT 2024-07-18 US claimed
WO-2024102465-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES SURMODICS, INC. (US) 2024-05-16 WO claimed
WO-2023172686-A1 THROMBORESISTANT COATINGS, COATED DEVICES, AND METHODS Surmodics Coatings, LLC (US) 2023-09-14 WO claimed
EP-3581213-B1 COATED MEDICAL DEVICE SURMODICS INC (US) 2022-07-06 EP claimed
US-10253193-B2 Photoactivatable crosslinker SURMODICS, INC. (US) 2019-04-09 US claimed
EP-2552927-B1 DEGRADABLE PHOTO-CROSSLINKERS SURMODICS INC (US) 2019-03-13 EP claimed
US-20180273773-A1 PHOTOACTIVATABLE CROSSLINKER BANK OF MONTREAL, AS COLLATERAL AGENT 2018-09-27 US claimed
EP-2804915-B1 LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES SURMODICS INC (US) 2016-03-30 EP claimed
WO-2026090506-A1 MEDICAL DEVICE COATINGS AND METHODS SURMODICS, INC. (US) 2026-04-30 WO disclosed
US-20260108662-A1 LUBRICIOUS COATING FOR MEDICAL DEVICE SURMODICS INC (US) 2026-04-23 US disclosed
US-20260098225-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES SURMODICS INC (US) 2026-04-09 US disclosed
US-12472288-B2 Lubricious coating for medical device SURMODICS, INC. (US) 2025-11-18 US disclosed
WO-2011123441-A1 DEGRADABLE PHOTO-CROSSLINKER SURMODICS, INC. (US) 2011-10-06 WO disclosed
WO-2011123441-A1 DEGRADABLE PHOTO-CROSSLINKER SURMODICS, INC. (US) 2011-10-06 WO disclosed
US-20110245367-A1 DEGRADABLE PHOTO-CROSSLINKER SURMODICS, INC. (US) 2011-10-06 US disclosed
US-20110245367-A1 DEGRADABLE PHOTO-CROSSLINKER SURMODICS, INC. (US) 2011-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108662-A1 LUBRICIOUS COATING FOR MEDICAL DEVICE MUC1, ADH1A, PTK2 ELANE 2306/4885ALDH1A1 45/4885SRD5A2 2043/4885
US-10253193-B2 Photoactivatable crosslinker GLO1, LCP1, PLOD1 ELANE 3717/4885ALDH1A1 1430/4885SRD5A2 2458/4885
US-20180273773-A1 PHOTOACTIVATABLE CROSSLINKER GLO1, LCP1, PLOD1 ELANE 3717/4885ALDH1A1 1430/4885SRD5A2 2458/4885
US-20260098225-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES CUTA, EED, SELP ELANE 1715/4885ALDH1A1 135/4885SRD5A2 1647/4885
US-20110245367-A1 DEGRADABLE PHOTO-CROSSLINKER LCP1, GLO1, PLOD1 ELANE 3629/4885ALDH1A1 1689/4885SRD5A2 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.