Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453670 | 0.75 | POLB (0.44) | KIF11POLBKEAP1NFE2L2CHRM2 | |
| SCHEMBL6452030 | 0.75 | CHRM2 (0.46) | POLBKEAP1NFE2L2CHRM2CHRM1 | |
| SCHEMBL3813339 | 0.70 | KEAP1 (0.46) | KIF11KEAP1NFE2L2CHRM2CHRM1 | |
| SCHEMBL28422850 | 0.66 | CHRM2 (0.42) | POLBKEAP1NFE2L2CHRM2CHRM1 | |
| SCHEMBL10370745 | 0.65 | CHRM2 (0.58) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL15412916 | 0.65 | KEAP1 (0.46) | KIF11KEAP1NFE2L2CHRM2CHRM1 | |
| SCHEMBL28428386 | 0.64 | CHRM2 (0.43) | POLBKEAP1NFE2L2CHRM2CHRM1 | |
| SCHEMBL21633894 | 0.64 | NPY2R (0.36) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL25610774 | 0.63 | CHRM2 (0.58) | KEAP1NFE2L2CHRM2CHRM1CHRM3 | |
| SCHEMBL27969478 | 0.63 | CHRM2 (0.58) | KEAP1NFE2L2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |