Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453670 | 0.79 | POLB (0.44) | CHRM2CHRM1KCNH2CYP2D6KEAP1 | |
| SCHEMBL10370745 | 0.78 | CHRM2 (0.58) | CHRM2CHRM1KCNH2CYP2D6KEAP1 | |
| SCHEMBL25610774 | 0.76 | CHRM2 (0.58) | CHRM2CHRM1KCNH2CYP2D6KEAP1 | |
| SCHEMBL27969478 | 0.76 | CHRM2 (0.58) | CHRM2CHRM1KCNH2CYP2D6KEAP1 | |
| SCHEMBL6449683 | 0.75 | KIF11 (0.36) | CHRM2CHRM1KCNH2CYP2D6KEAP1 | |
| SCHEMBL12238410 | 0.73 | KEAP1 (0.50) | CHRM2CHRM1KCNH2CYP2D6KEAP1 | |
| SCHEMBL12238412 | 0.73 | KEAP1 (0.50) | CHRM2CHRM1KCNH2CYP2D6KEAP1 | |
| SCHEMBL28422850 | 0.72 | CHRM2 (0.42) | CHRM2CHRM1KCNH2CYP2D6KEAP1 | |
| SCHEMBL23320576 | 0.72 | KCNN4 (0.39) | KCNH2CYP2D6CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL9906166 | 0.72 | KEAP1 (0.56) | CHRM2CHRM1KCNH2CYP2D6KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |