Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452038 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HPGDKDM4ETSHRKMT2A | |
| SCHEMBL6453675 | 0.78 | HPGD (0.43) | ALDH1A1HPGDCYSLTR2CYSLTR1HTR1A | |
| SCHEMBL28204665 | 0.69 | IDO1 (0.50) | KDM4EMEN1KMT2A | |
| SCHEMBL1446331 | 0.66 | KMT2A (0.51) | ALDH1A1MEN1KMT2A | |
| SCHEMBL31692849 | 0.65 | L3MBTL1 (0.36) | ALDH1A1CA1CA2MEN1KMT2A | |
| SCHEMBL22807502 | 0.64 | L3MBTL1 (0.41) | KMT2AEGFR | |
| SCHEMBL30741239 | 0.63 | CA12 (0.48) | ALDH1A1CA1CA2KDM4EEGFR | |
| SCHEMBL30741241 | 0.63 | CA12 (0.48) | ALDH1A1CA1CA2KDM4EEGFR | |
| SCHEMBL3185351 | 0.63 | CA12 (0.48) | ALDH1A1CA1CA2KDM4EEGFR | |
| SCHEMBL28140045 | 0.63 | PPARG (0.35) | ALDH1A1CA1CA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |