Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452038 | 0.80 | ALDH1A1 (0.39) | HPGDALDH1A1KMT2ATSHRKDM4E | |
| SCHEMBL6449684 | 0.78 | ALDH1A1 (0.36) | HPGDALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL28202626 | 0.76 | KDM4E (0.47) | KMT2AMEN1TSHRKDM4ELMNA | |
| SCHEMBL14862759 | 0.73 | KMT2A (0.45) | HPGDALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL2751914 | 0.69 | METAP2 (0.51) | ALDH1A1KCNH2CYP2D6 | |
| SCHEMBL5051927 | 0.69 | MEN1 (0.59) | KMT2AMEN1TSHRCYP3A4CHRM2 | |
| SCHEMBL3639348 | 0.69 | MEN1 (0.59) | KMT2AMEN1TSHRCYP3A4CHRM2 | |
| SCHEMBL14453324 | 0.69 | MEN1 (0.59) | KMT2AMEN1TSHRCYP3A4CHRM2 | |
| SCHEMBL14453320 | 0.69 | MEN1 (0.59) | KMT2AMEN1TSHRCYP3A4CHRM2 | |
| SCHEMBL8618823 | 0.68 | CTSS (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |