Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27159538 | 0.70 | — | — | |
| SCHEMBL28242345 | 0.70 | AKR1A1 (0.31) | — | |
| SCHEMBL18135469 | 0.68 | CHRNB2 (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1068404 | 0.65 | HTR2C (0.38) | — | |
| SCHEMBL15566855 | 0.64 | KDM1A (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL16553483 | 0.62 | PTGS1 (0.35) | — | |
| SCHEMBL2286902 | 0.62 | — | — | |
| SCHEMBL975333 | 0.62 | — | — | |
| SCHEMBL3611345 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL6390297 | 0.61 | CHRNB2 (0.76) | CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6964974-B2 | 2,3-oxidosqualene-lanosterol cyclase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2005-11-15 | — | — | US | disclosed |