Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.38 |
| ▸ | HTR1A | P08908 | 8/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432692 | 0.90 | PTGS2 (0.37) | HTR2CHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2783168 | 0.80 | DRD2 (0.40) | SLC6A4 | |
| SCHEMBL2784809 | 0.78 | DRD2 (0.55) | SLC6A4 | |
| SCHEMBL2782663 | 0.77 | SIGMAR1 (0.42) | HTR1ASLC6A4 | |
| SCHEMBL455259 | 0.76 | HTR2C (0.39) | HTR2C | |
| SCHEMBL16958502 | 0.76 | HTR2C (0.31) | HTR2C | |
| SCHEMBL9586481 | 0.76 | HTR2C (0.31) | HTR2C | |
| SCHEMBL2805088 | 0.74 | DRD2 (0.45) | HTR1ASLC6A4 | |
| SCHEMBL456171 | 0.74 | TP53 (0.33) | HTR2C | |
| SCHEMBL16960341 | 0.74 | HTR2C (0.31) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118265702-A | Microbiocidal isonicotinamide derivatives | 先正达农作物保护股份公司 | 2024-06-28 | — | — | CN | claimed |
| US-20240208902-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-06-27 | — | — | US | claimed |
| WO-2024132895-A1 | MICROBIOCIDAL DIHYDROOXADIAZINYL PYRIDAZINONE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-27 | — | — | WO | claimed |
| WO-2024132901-A1 | MICROBIOCIDAL PYRIDAZINE DIHYDROOXADIAZINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-27 | — | — | WO | claimed |
| WO-2024089191-A1 | MICROBIOCIDAL HETEROBICYCLIC DIHYDROOXADIAZINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-05-02 | — | — | WO | claimed |
| WO-2024068976-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2024-04-04 | — | — | WO | claimed |
| EP-4345101-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2024-04-03 | — | — | EP | claimed |
| US-20240016152-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-18 | — | — | US | claimed |
| US-11802111-B2 | Cyclobutyl amide monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-31 | — | — | US | claimed |
| EP-4217062-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | claimed |
| WO-2023089049-A2 | MICROBIOCIDAL ISONICOTINIC AMIDE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-25 | — | — | WO | claimed |
| EP-4167740-A1 | ACTIVE COMPOUND COMBINATIONS | Bayer Aktiengesellschaft (DE) | 2023-04-26 | — | — | EP | claimed |
| CN-115955916-A | Active compound combinations | 拜耳公司 | 2023-04-11 | — | — | CN | claimed |
| WO-2021255070-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-23 | — | — | WO | claimed |
| US-9890167-B2 | Pyrazine compounds for the treatment of infectious diseases | HOFFMANN-LA ROCHE INC. (US) | 2018-02-13 | — | — | US | claimed |
| EP-3245206-A1 | PYRAZINE COMPOUNDS FOR THE TREATMENT OF INFECTIOUS DISEASES | F. Hoffmann-La Roche AG (CH) | 2017-11-22 | — | — | EP | claimed |
| US-20160237090-A1 | NOVEL PYRAZINE COMPOUNDS FOR THE TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 2016-08-18 | — | — | US | claimed |
| WO-2016113273-A1 | PYRAZINE COMPOUNDS FOR THE TREATMENT OF INFECTIOUS DISEASES | F. HOFFMANN-LA ROCHE AG (CH) | 2016-07-21 | — | — | WO | claimed |
| US-7741327-B2 | Pyrrolidinone glucokinase activators | HOFFMANN-LA ROCHE INC. (US) | 2010-06-22 | — | — | US | claimed |
| US-20090264445-A1 | PYRROLIDINONE GLUCOKINASE ACTIVATORS | BERTHEL STEVEN JOSEPH | 2009-10-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016152-A1 | ACTIVE COMPOUND COMBINATIONS | CYP51A1, ERG28, BROX | HTR2C 4661/4885HTR1A 4719/4885SLC6A2 4686/4885 |
| US-20090264445-A1 | PYRROLIDINONE GLUCOKINASE ACTIVATORS | GCKR, GCK, PDK2 | HTR2C 3892/4885HTR1A 4454/4885SLC6A2 3967/4885 |
| US-20160237090-A1 | NOVEL PYRAZINE COMPOUNDS FOR THE TREATMENT OF INFECTIOUS DISEASES | HAVCR2, NR1H4, ZC3HAV1 | HTR2C 2259/4885HTR1A 2632/4885SLC6A2 4371/4885 |
| US-20240208902-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | MGLL, LPL, PNLIP | HTR2C 457/4885HTR1A 318/4885SLC6A2 1255/4885 |
| US-11802111-B2 | Cyclobutyl amide monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | HTR2C 438/4885HTR1A 315/4885SLC6A2 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.