Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28518568 | 0.92 | ACE2 (0.43) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL28703780 | 0.92 | ACE2 (0.43) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL28703782 | 0.92 | ACE2 (0.43) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL28856645 | 0.91 | MMP1 (0.42) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL28856644 | 0.91 | MMP1 (0.42) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL3200413 | 0.87 | HTR2A (0.41) | CA12CA9HTR2AHRH1PGR | |
| SCHEMBL7904494 | 0.87 | HTR2A (0.41) | CA12CA9HTR2AHRH1PGR | |
| SCHEMBL8524074 | 0.85 | ACE2 (0.42) | CA2MAPK1ACE2GPR84FFAR1 | |
| SCHEMBL10973416 | 0.85 | ACE2 (0.42) | CA2MAPK1ACE2GPR84FFAR1 | |
| SCHEMBL8523775 | 0.85 | ACE2 (0.42) | CA2MAPK1ACE2GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872401-B2 | Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil | L'OREAL (FR) | 2005-03-29 | — | — | US | disclosed |
| US-20040009200-A1 | Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil | SOCIETE L'OREAL S.A. (FR) | 2004-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009200-A1 | Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil | KRT18, DHCR24, FABP4 | CA12 3894/4885CA1 3726/4885CA9 4149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.