Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 2/20 | 0.42 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251127 | 0.75 | PIK3CA (0.44) | QPCTMAPTLMNAALDH1A1MEN1 | |
| SCHEMBL155447 | 0.72 | PDPK1 (0.41) | MAPTLMNAALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL17186359 | 0.70 | PDPK1 (0.40) | MAPTLMNAALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL17186229 | 0.70 | PDPK1 (0.40) | MAPTLMNAALDH1A1HPGDMEN1 | |
| SCHEMBL22524079 | 0.70 | ALDH1A1 (0.36) | ALDH1A1XDHDAOADORA3CYP1A2 | |
| SCHEMBL31226407 | 0.69 | QPCT (0.40) | QPCTMAPTLMNAALDH1A1HPGD | |
| SCHEMBL26529868 | 0.68 | LMNA (0.64) | MAPTLMNAALDH1A1HPGDMEN1 | |
| SCHEMBL31146869 | 0.68 | QPCT (0.48) | QTRT1QPCTMAPTLMNAALDH1A1 | |
| SCHEMBL17144480 | 0.68 | SLC2A1 (0.47) | QPCTMAPTLMNAALDH1A1MEN1 | |
| SCHEMBL5196594 | 0.67 | KDM4E (0.41) | QTRT1LIG1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539783-A1 | INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND NUCLEOSIDASES | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018496-A1 | INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND NUCLEOSIDASES | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2004-03-04 | — | — | WO | disclosed |