SCHEMBL155447

SCHEMBL155447

CN(C)c1nc2[nH]cnc2c(=O)[nH]1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 4/20 0.41
PNP P00491 1/20 0.38
LMNA P02545 3/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
MAT2A P31153 1/20 0.36
KDM4A O75164 1/20 0.36
KDM4B O94953 1/20 0.36
KDM5C P41229 1/20 0.36
KDM5B Q9UGL1 1/20 0.36
IP6K1 Q92551 2/20 0.34
PARP1 P09874 2/20 0.33
PMP22 Q01453 2/20 0.33
GDA Q9Y2T3 2/20 0.33
ACHE P22303 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
GLA P06280 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17186359 0.98 PDPK1 (0.40) PDPK1PNPLMNAKDM4EALDH1A1
Hydrochloric Acid SCHEMBL17186229 0.98 PDPK1 (0.40) PDPK1PNPLMNAKDM4EALDH1A1
SCHEMBL22524079 0.84 ALDH1A1 (0.36) PDPK1PNPALDH1A1KDM4AKDM4B
SCHEMBL17373198 0.79 ALDH1A1 (0.33) PDPK1LMNAKDM4EALDH1A1HPGD
SCHEMBL8278860 0.77 PARP1 (0.43) PDPK1PNPKDM4EALDH1A1PARP1
SCHEMBL30369209 0.74 GDA (0.35) PDPK1PNPLMNAKDM4EALDH1A1
SCHEMBL28969 0.74 PDPK1 (0.41) PDPK1PNPLMNAKDM4EALDH1A1
SCHEMBL30139079 0.73 PDPK1 (0.33) PDPK1PNPKDM4AKDM4BKDM5C
Guanine SCHEMBL4658042 0.73 ALDH1A1 (0.61) PNPLMNAKDM4EALDH1A1HPGD
SCHEMBL21896056 0.73 PNP (0.41) PDPK1PNPLMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
EP-4457513-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE Société des Produits Nestlé S.A. (CH) 2024-11-06 EP claimed
CN-115367745-B Tungsten-containing substance hybridization and nitrogen-doped porous carbon material and preparation method thereof 北京化工大学 2023-11-24 CN claimed
WO-2023126758-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE Société des Produits Nestlé S.A. (CH) 2023-07-06 WO claimed
US-20230204604-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE SOCIETE DES PRODUITS NESTLE S.A. (CH) 2023-06-29 US claimed
CN-115367745-A Tungsten-containing substance hybrid and nitrogen-doped porous carbon material and preparation method thereof 北京化工大学 2022-11-22 CN claimed
CN-115367726-A Oxygen-doped titanium nitride hybridized and nitrogen-doped porous carbon material and preparation method and application thereof 北京化工大学 2022-11-22 CN claimed
US-20220282275-A1 G-TO-T BASE EDITORS AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2022-09-08 US claimed
WO-2021238912-A1 TRANSITION METAL COMPOUND-HYBRIDIZED AND NITROGEN-DOPED POROUS CARBON MATERIAL AND PREPARATION METHOD THEREFOR 北京化工大学 2021-12-02 WO claimed
CN-111892047-A Vanadium nitride hybrid and nitrogen-doped porous carbon material and preparation method and application thereof 北京化工大学 2020-11-06 CN claimed
CN-1846674-A Slow released anticancer injection JINAN SHUIHUA MEDICINE SCI TEC (CN) 2006-10-18 CN claimed
CN-1733306-A Anticancer implantation agent containing blood vessel inhibitor and guanine similarities KONG QINGZHONG (CN) 2006-02-15 CN claimed
CN-1679947-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679944-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679951-A Medicinal composition for tumor body LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679945-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679946-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679936-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1628852-A Anti solid tumor medicine composition KONG QINGZHONG (CN) 2005-06-22 CN claimed
US-20040009602-A1 DNA modifying molecules and methods of use thereof THE GOVERNMENT OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICES 2004-01-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease GLS, AADAT, FGF23 PDPK1 1413/4885PNP 241/4885LMNA 1592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.