Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3201232 | 0.85 | ALB (0.49) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL30366389 | 0.85 | ALB (0.49) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL9207720 | 0.84 | FTO (0.38) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL917141 | 0.84 | ALB (0.58) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL3499473 | 0.84 | ALB (0.56) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL20353152 | 0.81 | FTO (0.55) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL2498538 | 0.81 | FTO (0.55) | ALBFTOKCNH2MMP14MEN1 | |
| SCHEMBL31172568 | 0.81 | ALB (0.55) | ALBFTOKCNH2MMP14JAK2 | |
| Isothiocyanate SCHEMBL27141128 | 0.79 | ALB (0.54) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL24943573 | 0.79 | FTO (0.57) | ALBFTOKCNH2MMP14JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546371-A1 | SUBSTRATES FOR O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031405-A1 | SUBSTRATES FOR O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2004-04-15 | — | — | WO | disclosed |