Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | THRB | P10828 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | G6PD | P11413 | 1/20 | 0.74 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127980 | 0.85 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL4467416 | 0.81 | ALDH1A1 (0.90) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL5804362 | 0.78 | KDM4E (0.68) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL24582730 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL8389821 | 0.76 | ALDH1A1 (0.71) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL11272081 | 0.76 | ALDH1A1 (0.71) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL7292985 | 0.74 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL6128132 | 0.74 | KDM4E (0.61) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL12806791 | 0.73 | BACE1 (0.45) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL11792241 | 0.73 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903239-B2 | Fluorinated benzaldehydes | BAYER CHEMICAL AKTIENGESELLSCHAFT (DE) | 2005-06-07 | — | — | US | claimed |
| US-20040171864-A1 | Fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-02 | — | — | US | claimed |
| US-20040133043-A1 | Fluorinated benzaldehydes | LANXESS DEUTSCHLAND GMBH (DE) | 2004-07-08 | — | — | US | claimed |
| EP-1431279-A2 | Fluoride containing aromatic compounds | Bayer Chemicals AG (DE) | 2004-06-23 | — | — | EP | claimed |
| EP-1428814-A1 | Fluorine containing benzaldehydes | Bayer Chemicals AG (DE) | 2004-06-16 | — | — | EP | claimed |
| US-6903239-B2 | Fluorinated benzaldehydes | BAYER CHEMICAL AKTIENGESELLSCHAFT (DE) | 2005-06-07 | — | — | US | disclosed |
| US-20040171864-A1 | Fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-02 | — | — | US | disclosed |
| US-20040133043-A1 | Fluorinated benzaldehydes | LANXESS DEUTSCHLAND GMBH (DE) | 2004-07-08 | — | — | US | disclosed |
| EP-1431279-A2 | Fluoride containing aromatic compounds | Bayer Chemicals AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| EP-1428814-A1 | Fluorine containing benzaldehydes | Bayer Chemicals AG (DE) | 2004-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133043-A1 | Fluorinated benzaldehydes | PFAS, FIP1L1, AFF2 | ALDH1A1 25/4885KDM4E 1421/4885MAPT 2360/4885 |
| US-20040171864-A1 | Fluorinated aromatics | AFF1, AFF2, AFF4 | ALDH1A1 1595/4885KDM4E 585/4885MAPT 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.