Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | GALR1 | P47211 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460828 | 0.94 | CYP19A1 (0.43) | IDH1HSD11B1GALR2GALR1NFE2L2 | |
| SCHEMBL6450174 | 0.90 | HSD11B1 (0.42) | HSD11B1GALR2GALR1NFE2L2MEN1 | |
| SCHEMBL6454408 | 0.84 | IDH1 (0.46) | IDH1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6451311 | 0.83 | SYK (0.40) | HSD11B1NPC1RAB9APDE4APDE4B | |
| SCHEMBL6449976 | 0.82 | EPHX2 (0.41) | HSD11B1MEN1KMT2AKDM4ECAPN1 | |
| SCHEMBL6452335 | 0.81 | GABRA1 (0.41) | HSD11B1NFE2L2ALDH1A1MAPTKDM4E | |
| SCHEMBL6449993 | 0.79 | EPHX2 (0.36) | HSD11B1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6454650 | 0.78 | HSD11B1 (0.41) | IDH1HSD11B1GALR2GALR1NFE2L2 | |
| SCHEMBL6448695 | 0.77 | MAPT (0.50) | IDH1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6454162 | 0.77 | CYP19A1 (0.46) | IDH1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | ANADYS PHARMACEUTICALS, INC. (US) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | HAVCR2, HCCS, LIPC | IDH1 89/4885HSD11B1 357/4885GALR2 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.