SCHEMBL6451104

SCHEMBL6451104

Nc1cccc(C(=O)c2cccc(C(=O)O)c2)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.78
NPC1 O15118 1/20 0.61
MITF O75030 1/20 0.61
LMNA P02545 1/20 0.61
POLB P06746 1/20 0.61
ATM Q13315 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA9 Q16790 3/20 0.53
CA12 O43570 1/20 0.50
CA6 P23280 1/20 0.50
SRD5A2 P31213 2/20 0.48
KMO O15229 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
F2 P00734 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL8764875 0.94 PBRM1 (0.88) PBRM1NPC1MITFLMNAPOLB
3-Aminobenzoic Acid SCHEMBL27648 0.92 PBRM1 (0.69) PBRM1NPC1MITFLMNAPOLB
3-Aminobenzoic Acid SCHEMBL8003706 0.92 PBRM1 (0.69) PBRM1NPC1MITFLMNAPOLB
3-Aminobenzoic Acid SCHEMBL29367812 0.92 PBRM1 (0.69) PBRM1NPC1MITFLMNAPOLB
SCHEMBL9101086 0.92 PBRM1 (0.83) PBRM1NPC1MITFLMNAPOLB
SCHEMBL204263 0.92 PBRM1 (0.83) PBRM1NPC1MITFLMNAPOLB
SCHEMBL29492479 0.92 PBRM1 (0.83) PBRM1NPC1MITFLMNAPOLB
SCHEMBL6865179 0.90 PBRM1 (0.81) PBRM1NPC1MITFLMNAPOLB
3-Aminobenzoic Acid SCHEMBL11796891 0.90 PBRM1 (0.67) PBRM1NPC1MITFLMNAPOLB
3-Aminobenzoic Acid SCHEMBL1478325 0.90 PBRM1 (0.67) PBRM1NPC1MITFLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9029496-B2 Liquid crystal polyester amide resin POLYPLASTICS CO., LTD. (JP) 2015-05-12 US disclosed
US-20140256903-A1 LIQUID CRYSTAL POLYESTER AMIDE RESIN POLYPLASTICS CO., LTD. (JP) 2014-09-11 US disclosed
WO-2005097868-A1 ESTERAMIDE COMPOSITIONS, COPOLYMERS AND BLENDS THEREOF GENERAL ELECTRIC COMPANY (US) 2005-10-20 WO disclosed
US-20050228122-A1 Esteramide compositions, copolymers and blends thereof GENERAL ELECTRIC COMPANY 2005-10-13 US disclosed
US-5811495-A Esteramide copolymers and production thereof TOSOH CORPORATION (JP) 1998-09-22 US disclosed
EP-0608976-B1 Esteramide copolymers and production thereof TOSOH CORP (JP) 1997-11-12 EP disclosed
EP-0608976-A1 Esteramide copolymers and production thereof Tosoh Corporation (JP) 1994-08-03 EP disclosed