Benzene

Benzene

SCHEMBL8764875

Nc1cccc(C(=O)c2cccc(C(=O)c3cccc(N)c3)c2)c1.c1ccccc1

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.88
TDP1 Q9NUW8 2/20 0.67
ATM Q13315 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
NPC1 O15118 1/20 0.67
MITF O75030 1/20 0.67
LMNA P02545 1/20 0.67
POLB P06746 1/20 0.67
CA1 P00915 3/20 0.57
CA2 P00918 3/20 0.57
CA9 Q16790 3/20 0.57
F2 P00734 1/20 0.52
PLG P00747 1/20 0.52
PRSS1 P07477 1/20 0.52
PRSS2 P07478 1/20 0.52
PRSS3 P35030 1/20 0.52
ALDH1A1 P00352 3/20 0.50
CYP3A4 P08684 1/20 0.48
CASP1 P29466 1/20 0.48
RECQL P46063 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9101086 0.98 PBRM1 (0.83) PBRM1TDP1ATML3MBTL1NPC1
SCHEMBL204263 0.98 PBRM1 (0.83) PBRM1TDP1ATML3MBTL1NPC1
SCHEMBL29492479 0.98 PBRM1 (0.83) PBRM1TDP1ATML3MBTL1NPC1
Hydrochloric Acid SCHEMBL8962669 0.95 PBRM1 (0.80) PBRM1TDP1ATML3MBTL1NPC1
SCHEMBL29363032 0.95 PBRM1 (0.87) PBRM1TDP1ATML3MBTL1NPC1
SCHEMBL125621 0.95 PBRM1 (0.87) PBRM1TDP1ATML3MBTL1NPC1
SCHEMBL9282073 0.95 PBRM1 (0.87) PBRM1TDP1ATML3MBTL1NPC1
SCHEMBL6451104 0.94 PBRM1 (0.78) PBRM1TDP1ATML3MBTL1NPC1
SCHEMBL147608 0.93 PBRM1 (1.00) PBRM1TDP1ATML3MBTL1NPC1
Hydrochloric Acid SCHEMBL8643223 0.93 PBRM1 (0.83) PBRM1TDP1ATML3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0572196-B1 Polyimide, and preparation process of same MITSUI TOATSU CHEMICALS (JP) 1997-08-06 EP disclosed