SCHEMBL204263

SCHEMBL204263

Nc1cccc(C(=O)c2cccc(C(=O)c3cccc(N)c3)c2)c1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.83
NPC1 O15118 1/20 0.69
MITF O75030 1/20 0.69
LMNA P02545 1/20 0.69
POLB P06746 1/20 0.69
TDP1 Q9NUW8 2/20 0.62
ATM Q13315 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA9 Q16790 2/20 0.59
F2 P00734 1/20 0.54
PLG P00747 1/20 0.54
PRSS1 P07477 1/20 0.54
PRSS2 P07478 1/20 0.54
PRSS3 P35030 1/20 0.54
CYP3A4 P08684 1/20 0.50
CASP1 P29466 1/20 0.50
RECQL P46063 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9101086 1.00 PBRM1 (0.83) PBRM1NPC1MITFLMNAPOLB
SCHEMBL29492479 1.00 PBRM1 (0.83) PBRM1NPC1MITFLMNAPOLB
Hydrochloric Acid SCHEMBL8962669 0.98 PBRM1 (0.80) PBRM1NPC1MITFLMNAPOLB
Benzene SCHEMBL8764875 0.98 PBRM1 (0.88) PBRM1NPC1MITFLMNAPOLB
SCHEMBL29363032 0.98 PBRM1 (0.87) PBRM1NPC1MITFLMNAPOLB
SCHEMBL125621 0.98 PBRM1 (0.87) PBRM1NPC1MITFLMNAPOLB
SCHEMBL9282073 0.98 PBRM1 (0.87) PBRM1NPC1MITFLMNAPOLB
Hydrochloric Acid SCHEMBL8643223 0.95 PBRM1 (0.83) PBRM1NPC1MITFLMNAPOLB
SCHEMBL203373 0.93 PBRM1 (0.88) PBRM1NPC1MITFLMNAPOLB
SCHEMBL29492473 0.93 PBRM1 (0.88) PBRM1NPC1MITFLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180333347-A1 PHOTOCHEMICALLY STABLE, NON-LEACHING SUNSCREENS FROM EPOXIDE-BASED SILANE COUPLING AGENTS AND UV ABSORBING CHROMOPHORES ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2018-11-22 US claimed
US-6040418-A FLUORINATED POLYMIDES COMPRISING UNITS OF 2,2',5,5',6,6'-HEXAFLUOROBIPHENYL-3,3',4,4'-TETRACARBOXYLIC DIANHYDRIDE AND AROMATIC DIAMINE UBE INDUSTRIES, LTD. (JP) 2000-03-21 US claimed
EP-0474501-B1 Aromatic diamine compound, preparation process of same and polyimide prepared from same MITSUI TOATSU CHEMICALS (JP) 1996-02-14 EP claimed
US-5322962-A Produce polyimides with high heat and chemical resistance, processability MITSUI TOATSU CHEMICALS, INC. (JP) 1994-06-21 US claimed
EP-0474501-A1 Aromatic diamine compound, preparation process of same and polyimide prepared from same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-03-11 EP claimed
US-12504687-B2 Curable photosensitive resin composition, cured product, resist pattern, method of producing resist pattern, semiconductor device and electronic device ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 2025-12-23 US disclosed
US-20250382418-A1 DISPLAY PANEL, ALIGNMENT FILM COMPOSITION AND DISPLAY DEVICE Guangzhou China Star Optoelectronics Semiconductor Display Technology Co., Ltd. (CN) 2025-12-18 US disclosed
US-20250346020-A1 LAMINATE AND DISPLAY KANEKA CORPORATION (JP) 2025-11-13 US disclosed
US-20250320338-A1 TRANSPARENT FILM, HARD COAT FILM, AND DISPLAY KANEKA CORPORATION (JP) 2025-10-16 US disclosed
US-20250282996-A1 ALIGNMENT FILM COMPOSITION, DISPLAY PANEL AND METHOD OF MANUFACTURE THEREOF TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2025-09-11 US disclosed
US-12343424-B2 Photochemically stable, non-leaching, bridged polysilsesquioxane based sunscreens ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2025-07-01 US disclosed
WO-2025074873-A1 POLYAMIDIMIDE, RESIN COMPOSITION, MOLDED ARTICLE, AND FILM 株式会社カネカ 2025-04-10 WO disclosed
US-5231160-A AROMATIC DIAMINE COMPOUND, PREPARATION PROCESS OF SAME AND POLYIMIDE PREPARED FROM SAME MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-07-27 US disclosed
US-5231160-A AROMATIC DIAMINE COMPOUND, PREPARATION PROCESS OF SAME AND POLYIMIDE PREPARED FROM SAME MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-07-27 US disclosed
EP-0518543-A2 Polyimide and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-12-16 EP disclosed
EP-0474501-A1 Aromatic diamine compound, preparation process of same and polyimide prepared from same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-03-11 EP disclosed
EP-0474501-A1 Aromatic diamine compound, preparation process of same and polyimide prepared from same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-03-11 EP disclosed
US-4837280-A ACRYLATE GROUP-CONTAINING POLYAROMATIC AMINE COMPOUNDS TO FORM THERMOSETTING RESINS; HEAT RESISTANCE NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1989-06-06 US disclosed
US-4686250-A AS HARDNER AMOCO CORPORATION (US) 1987-08-11 US disclosed
EP-0228277-A2 Moisture resistant, wet winding epoxy resin system containing aromatic diamines AMOCO CORPORATION (US) 1987-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12343424-B2 Photochemically stable, non-leaching, bridged polysilsesquioxane based sunscreens SQLE, STS, DSG1 PBRM1 1581/4885NPC1 2932/4885MITF 510/4885
US-20180333347-A1 PHOTOCHEMICALLY STABLE, NON-LEACHING SUNSCREENS FROM EPOXIDE-BASED SILANE COUPLING AGENTS AND UV ABSORBING CHROMOPHORES CCNE2, SUN2, CCNE1 PBRM1 1833/4885NPC1 1940/4885MITF 560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.