SCHEMBL6451173

SCHEMBL6451173

CCCCC(=CN)C(=O)N(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
CES1 P23141 6/20 0.39
CES2 O00748 5/20 0.39
TP53 P04637 2/20 0.37
CA1 P00915 1/20 0.35
DNM1 Q05193 3/20 0.33
MEN1 O00255 1/20 0.33
FAAH O00519 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
SOAT1 P35610 1/20 0.33
KMT2A Q03164 1/20 0.33
EPHX2 P34913 1/20 0.33
AKR1B1 P15121 1/20 0.32
CNR1 P21554 1/20 0.32
TSHR P16473 1/20 0.31
SLC22A6 Q4U2R8 1/20 0.31
SLC22A8 Q8TCC7 1/20 0.31
GPR84 Q9NQS5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19212521 0.92 CES2 (0.43) ALDH1A1CES1CES2TP53DNM1
SCHEMBL197706 0.88 ALDH1A1 (0.37) ALDH1A1CES1CES2TSHR
SCHEMBL886933 0.79 ALDH1A1 (0.30) ALDH1A1
Hydrochloric Acid SCHEMBL5506899 0.77
SCHEMBL5528823 0.77 CES1 (0.44) ALDH1A1CES1CES2TP53CA1
SCHEMBL20163589 0.77 CES1 (0.44) ALDH1A1CES1CES2TP53CA1
SCHEMBL15641313 0.72 CES1 (0.39) ALDH1A1CES1CES2TP53CA1
SCHEMBL3355745 0.72 CES1 (0.39) ALDH1A1CES1CES2TP53CA1
SCHEMBL7657118 0.71 AKR1B1 (0.50) ALDH1A1CES1CES2MEN1CYP1A2
SCHEMBL7657108 0.71 AKR1B1 (0.50) ALDH1A1CES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1509568-A1 RUBBER MIXTURES CONTAINING QUATERNARY POLYMERS AND POLAR SOFTENING AGENTS Lanxess Deutschland GmbH (DE) 2005-03-02 EP disclosed
WO-2003099921-A1 RUBBER MIXTURES CONTAINING QUATERNARY POLYMERS AND POLAR SOFTENING AGENTS LANXESS DEUTSCHLAND GMBH (DE) 2003-12-04 WO disclosed
WO-2002020632-A1 QUATERNARY POLYMERS WITH FUNCTIONAL AMINE GROUPS BAYER AKTIENGESELLSCHAFT (DE) 2002-03-14 WO disclosed