Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.50 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448406 | 0.81 | TLR7 (0.56) | P2RX1TLR7KDM4EALDH1A1MEN1 | |
| SCHEMBL6467701 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1NFE2L2MEN1KMT2AMAPT | |
| SCHEMBL6449695 | 0.76 | RAB9A (0.66) | TLR7FADS1KDM4EALDH1A1KMT2A | |
| SCHEMBL6449845 | 0.76 | TMPRSS4 (0.55) | TMPRSS4P2RX1FADS1KDM4EALDH1A1 | |
| SCHEMBL6452299 | 0.75 | L3MBTL1 (0.51) | TLR7ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL6448795 | 0.73 | KAT6A (0.54) | TLR7KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL8709049 | 0.73 | MAPT (0.53) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6450508 | 0.72 | RAB9A (0.64) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2346222 | 0.71 | L3MBTL1 (0.55) | TLR7ALDH1A1NFE2L2L3MBTL1GAA | |
| SCHEMBL6449122 | 0.70 | TLR7 (0.47) | TLR7KDM4ETRPM8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | ANADYS PHARMACEUTICALS, INC. (US) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075375-A1 | Heterocyclic compounds for treating hepatitis C virus | HAVCR2, HCCS, LIPC | TMPRSS4 1403/4885P2RX1 2051/4885TLR7 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.