SCHEMBL645133

SCHEMBL645133

CN(C)CCC(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL729304 0.97
SCHEMBL2143745 0.83
Hydrochloric Acid SCHEMBL731554 0.81 ALDH1A1 (0.50)
SCHEMBL6643858 0.79 ALDH1A1 (0.56)
Hydrochloric Acid SCHEMBL4575270 0.78 ALDH1A1 (0.54)
Hydrochloric Acid SCHEMBL4573460 0.78 ALDH1A1 (0.54)
SCHEMBL3820149 0.76 TSHR (0.42)
SCHEMBL9233585 0.75 MAPT (0.42)
SCHEMBL9512763 0.75 CES2 (0.42)
SCHEMBL4593050 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116673006-B Preparation process and application of composite adsorption film material 上海惊叹化学有限公司 2023-09-29 CN claimed
CN-116673006-A Preparation process and application of composite adsorption film material 上海惊叹化学有限公司 2023-09-01 CN claimed
CN-112209976-B Decitabine intermediate compound V 鲁南制药集团股份有限公司 2023-05-26 CN claimed
CN-112209976-A Decitabine intermediate compound V 鲁南制药集团股份有限公司 2021-01-12 CN claimed
EP-4743440-A1 IONIZABLE LIPIDS eTheRNA immunotherapies NV (BE) 2026-05-20 EP disclosed
US-12605399-B2 Compositions for CFTR MRNA therapy TRANSLATE BIO, INC. (US) 2026-04-21 US disclosed
US-12576030-B2 Compositions for delivery of codon-optimized mRNA TRANSLATE BIO, INC. (US) 2026-03-17 US disclosed
US-20260060926-A1 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME SAIL BIOMEDICINES INC (US) 2026-03-05 US disclosed
US-20250276972-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS GRITSCIENCE BIOPHARMACEUTICALS CO LTD (CN) 2025-09-04 US disclosed
US-12404243-B2 Inhibitors of the Wnt/beta-catenin pathway THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-09-02 US disclosed
EP-3749640-B1 INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY UNIV CALIFORNIA (US) 2025-07-16 EP disclosed
EP-4581012-A2 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME Sail Biomedicines, Inc. (US) 2025-07-09 EP disclosed
US-20040176361-A1 Fused heterocyclic compound and medicinal use thereof MITSUBISHI PHARMA CORPORATION (JP) 2004-09-09 US disclosed
WO-2004037978-A2 METHODS OF REDUCING THE ACTIVITY OF AND REDUCING THE CONCENTRATION OF A MUTANT KIT PROTEIN THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2004-05-06 WO disclosed
EP-1396488-A1 FUSED HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF Mitsubishi Pharma Corporation (JP) 2004-03-10 EP disclosed
US-6632958-B1 An alkene (1) is added to cyclopentenone (2) under the action of an alkyl lithium and an organic copper reagent to form an adduct, said adduct is reacted with e.g. a carboxylic anhydride (4) to obtain a prostaglandin derivative, which is MITSUBISHI PHARMA CORPORATION (JP) 2003-10-14 US disclosed
US-6548515-B1 Use as anticancer agents LES LABORATORIES SERVIER (FR) 2003-04-15 US disclosed
WO-2002036574-A1 GELDANAMYCIN DERIVATIVES USEFUL FOR THE TREATMENT OF CANCER THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2002-05-10 WO disclosed
EP-1085012-A1 PROCESS FOR PRODUCING PURIFIED PROSTAGLANDIN DERIVATIVE Asahi Glass Co., Ltd. (JP) 2001-03-21 EP disclosed
US-5777114-A Spiro heterocycle-imidazo 1,2-a!indeno 1,2-e!pyrazine!-4'-ones, preparation thereof and drugs containing same RHONE-POULENC RORER S.A. (FR) 1998-07-07 US disclosed