SCHEMBL645223

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14204739	0.91	CYP3A4 (0.46)	CNR2POLBXDHTDP1L3MBTL1
	SCHEMBL643290	0.89	LMNA (0.56)	CNR2POLBXDHTDP1L3MBTL1
	SCHEMBL11506138	0.87	PTGS2 (0.58)	CNR2POLBTDP1L3MBTL1KDM4E
	SCHEMBL11506864	0.84	CNR2 (0.48)	CNR2POLBXDHTDP1L3MBTL1
	SCHEMBL643051	0.84	LMNA (0.50)	CNR2POLBXDHTDP1L3MBTL1
	SCHEMBL3548293	0.79	POLB (0.48)	CNR2POLBXDHTDP1L3MBTL1
	SCHEMBL643614	0.79	CNR2 (0.49)	CNR2POLBXDHTDP1L3MBTL1
	SCHEMBL3543111	0.78	TSHR (0.47)	TDP1L3MBTL1KDM4ECYP3A4ALDH1A1
	SCHEMBL643143	0.77	EGFR (0.42)	POLBXDHTDP1L3MBTL1LMNA
	SCHEMBL7828001	0.76	CYP3A4 (0.50)	POLBCYP3A4ALDH1A1ALOX5AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.