Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931659 | 0.87 | POLB (0.53) | CYP3A4ALDH1A1ALOX5ARPTGS1 | |
| SCHEMBL743276 | 0.83 | ERN1 (0.57) | CYP3A4ERN1SMN1; SMN2USP2MAPK1 | |
| SCHEMBL24804436 | 0.81 | CYP19A1 (0.54) | CYP3A4ALOX5ERN1SMN1; SMN2USP2 | |
| SCHEMBL11506306 | 0.78 | PTPN1 (0.41) | CYP3A4ALDH1A1ALOX5ARPTGS1 | |
| SCHEMBL11506138 | 0.78 | PTGS2 (0.58) | CYP3A4ALDH1A1ALOX5ARPTGS1 | |
| SCHEMBL644524 | 0.76 | POLB (0.49) | CYP3A4ALDH1A1ALOX5ARPTGS1 | |
| SCHEMBL6506991 | 0.76 | POLB (0.41) | CYP3A4ALDH1A1ALOX5ARPTGS1 | |
| SCHEMBL645223 | 0.76 | CNR2 (0.49) | CYP3A4ALDH1A1ALOX5ARPTGS1 | |
| SCHEMBL9247341 | 0.76 | POLB (0.46) | CYP3A4ALDH1A1ALOX5ARPTGS1 | |
| SCHEMBL7115040 | 0.75 | HMGCR (0.50) | CYP3A4ALOX5ERN1SMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075470-A1 | NOVEL ANALGESIC AND IMMUNOMODULATORY CANNABINOIDS | THE UNIVERSITY OF CONNECTICUT (US) | 2001-02-14 | — | — | EP | disclosed |
| WO-1999057106-A1 | NOVEL ANALGESIC AND IMMUNOMODULATORY CANNABINOIDS | THE UNIVERSITY OF CONNECTICUT (US) | 1999-11-11 | — | — | WO | disclosed |