Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452768 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL6461267 | 0.95 | KDM1A (0.43) | ALDH1A1MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL6461265 | 0.95 | KDM1A (0.43) | ALDH1A1MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL6460760 | 0.87 | APP (0.41) | KDM1AMAOAMAOBDRD2TRPV1 | |
| SCHEMBL6460762 | 0.87 | APP (0.41) | KDM1AMAOAMAOBDRD2TRPV1 | |
| SCHEMBL6453902 | 0.84 | RAB9A (0.42) | MAOAMAOBNPC1RAB9AESR2 | |
| SCHEMBL6453900 | 0.84 | RAB9A (0.42) | MAOAMAOBNPC1RAB9AESR2 | |
| SCHEMBL170548 | 0.84 | ESR2 (0.53) | ALDH1A1MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL6451772 | 0.83 | FASN (0.41) | KDM1AMAOAMAOBSLC6A2SLC6A4 | |
| SCHEMBL6451768 | 0.83 | FASN (0.41) | KDM1AMAOAMAOBSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |