Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | DBH | P09172 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10121174 | 0.87 | KDM4E (0.62) | KDM4EDBHGAARECQLHDAC1 | |
| SCHEMBL195312 | 0.86 | CYP2C9 (0.53) | KDM4EDBHGAARECQLRXRA | |
| SCHEMBL20185541 | 0.82 | KDM4E (0.48) | KDM4EDBHGAARECQLCYP2C9 | |
| SCHEMBL25524701 | 0.82 | KDM4E (0.48) | KDM4EDBHGAARECQLCYP2C9 | |
| SCHEMBL2940523 | 0.80 | PTGS2 (0.57) | KDM4EDBHGAARECQLESR1 | |
| SCHEMBL21284253 | 0.80 | KDM4E (0.47) | KDM4EDBHGAARECQLCYP2C9 | |
| SCHEMBL29390838 | 0.80 | PTGS2 (0.57) | KDM4EDBHGAARECQLESR1 | |
| SCHEMBL10941943 | 0.80 | KDM4E (0.56) | KDM4EDBHGAARECQLESR1 | |
| SCHEMBL12418688 | 0.80 | KDM4E (0.56) | KDM4EDBHGAARECQLPDCD1 | |
| SCHEMBL24654394 | 0.79 | KDM4E (0.46) | KDM4EDBHGAARECQLCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523506-A1 | NEW DIFUNCTIONAL PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2005-04-20 | — | — | EP | disclosed |
| WO-2004009651-A1 | NEW DIFUNCTIONAL PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-01-29 | — | — | WO | disclosed |