Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299041 | 0.78 | KDM4E (0.44) | DPP4DPP8DPP9DPP7KDM4E | |
| SCHEMBL4299039 | 0.77 | DPP4 (0.47) | DPP4DPP8DPP9DPP7KDM4E | |
| SCHEMBL2603213 | 0.75 | ACHE (0.55) | DPP4DPP8DPP9DPP7KDM4E | |
| SCHEMBL1146193 | 0.75 | DKK1 (0.55) | DPP4DPP8DPP9DPP7KDM4E | |
| SCHEMBL8281002 | 0.74 | DPP4 (0.60) | DPP4DPP8DPP9DPP7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8127062 | 0.74 | DKK1 (0.53) | DPP4DPP8DPP9DPP7KDM4E | |
| SCHEMBL23005918 | 0.72 | KDM4E (0.49) | DPP4DPP8DPP9DPP7KDM4E | |
| SCHEMBL4418417 | 0.72 | KDM4E (0.49) | DPP4DPP8DPP9DPP7KDM4E | |
| SCHEMBL2070684 | 0.72 | KDM4E (0.56) | KDM4ECYP2C19ALDH1A1LMNAMAPT | |
| SCHEMBL4497905 | 0.72 | KDM4E (0.45) | DPP4DPP8DPP9DPP7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499277-A4 | MODIFICATION OF FEEDING BEHAVIOR | IMP COLLEGE INNOVATIONS LTD (GB) | 2005-08-31 | — | — | EP | disclosed |
| EP-1499277-A2 | MODIFICATION OF FEEDING BEHAVIOR | Imperial College Innovations Limited (GB) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003026591-A2 | MODIFICATION OF FEEDING BEHAVIOR | IMPERIAL COLLEGE INNOVATIONS LTD. (GB) | 2003-04-03 | — | — | WO | disclosed |