Sugi Predict

Sugi Predict / Compounds / SCHEMBL2070684

SCHEMBL2070684

SCHEMBL2070684

NC1CCN(c2ncccn2)CC1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.56
▸ CYP2C19 P33261 1/20 0.56
▸ DKK1 O94907 1/20 0.51
▸ ALDH1A1 P00352 1/20 0.50
▸ RET P07949 1/20 0.49
▸ HRH3 Q9Y5N1 1/20 0.49
▸ LMNA P02545 2/20 0.48
▸ MAPT P10636 1/20 0.48
▸ USP2 O75604 1/20 0.46
▸ POLB P06746 1/20 0.46
▸ CYP2D6 P10635 2/20 0.44
▸ TSHR P16473 2/20 0.44
▸ HTR3E A5X5Y0 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ HTR3B O95264 1/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ ALOX15 P16050 1/20 0.44
▸ NFKB1 P19838 1/20 0.44
▸ HTR3A P46098 1/20 0.44
▸ KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17025657 0.98 KDM4E (0.55) KDM4ECYP2C19DKK1ALDH1A1RET
Hydrochloric Acid SCHEMBL5219864 0.98 KDM4E (0.55) KDM4ECYP2C19DKK1ALDH1A1RET
SCHEMBL4760428 0.88 DYRK1A (0.49) KDM4ECYP2C19DKK1ALDH1A1RET
SCHEMBL18239359 0.88 DYRK1A (0.49) KDM4ECYP2C19DKK1ALDH1A1RET
Hydrochloric Acid SCHEMBL26086991 0.86 DYRK1A (0.48) KDM4ECYP2C19DKK1ALDH1A1RET
Hydrochloric Acid SCHEMBL18228230 0.86 DYRK1A (0.48) KDM4ECYP2C19DKK1ALDH1A1RET
Hydrochloric Acid SCHEMBL26086988 0.86 DYRK1A (0.48) KDM4ECYP2C19DKK1ALDH1A1RET
SCHEMBL26504624 0.82 HRH3 (0.45) KDM4ECYP2C19DKK1RETHRH3
SCHEMBL7458987 0.81 DRD2 (0.44) KDM4ECYP2C19ALDH1A1LMNAMAPT
SCHEMBL7898534 0.81 DRD2 (0.44) KDM4ECYP2C19ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2079727-B1 KINASE INHIBITOR COMPOUNDS XCOVERY INC (US) 2016-02-17 — — EP claimed
US-8524709-B2 Kinase inhibitor compounds TYROGENEX, INC. (US) 2013-09-03 — — US claimed
US-20120115866-A1 KINASE INHIBITOR COMPOUNDS TYROGENEX, INC. (US) 2012-05-10 — — US claimed
US-7683057-B2 5-[5-fluoro-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (1-acetyl-piperidin-4-yl)-amide; inhibition of 5' AMP-activated protein kinase (AMPK) TYROGENEX, INC. (US) 2010-03-23 — — US claimed
US-20090076005-A1 Kinase inhibitor compounds XCOVERY, INC. (US) 2009-03-19 — — US claimed
EP-4169575-B1 CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS SATO PHARMA (JP) 2026-01-07 — — EP disclosed
US-12509444-B2 Compounds and methods for CD73 modulation and indications therefor PLEXXIKON INC. (US) 2025-12-30 — — US disclosed
WO-2025229624-A2 NEW CD38 INHIBITORS NAPA THERAPEUTICS LIMITED (GB) 2025-11-06 — — WO disclosed
CN-115667259-B Fused ring compounds for inhibiting H-PGDS 佐藤制药株式会社 2025-06-17 — — CN disclosed
US-20230339937-A1 CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS SATO PHARMACEUTICAL CO., LTD. (JP) 2023-10-26 — — US disclosed
EP-4169575-A1 CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS Sato Pharmaceutical Co., Ltd. (JP) 2023-04-26 — — EP disclosed
CN-115667259-A Condensed ring compounds for inhibiting H-PGDS 佐藤制药株式会社 2023-01-31 — — CN disclosed
US-7238688-B2 Piperidine compounds SCHERING CORPORATION (US) 2007-07-03 — — US disclosed
CN-1891689-A Aliphatic nitrogen - containing 5 - membered ring compound TANABE SEIYAKU CO (JP) 2007-01-10 — — CN disclosed
US-7138397-B2 Nitrogenous 5-membered ring compounds TANABE SEIYAKU CO., LTD. (JP) 2006-11-21 — — US disclosed
US-20060241146-A1 Nitrogen-containing 5-membered ring compound TANABE SEIYAKU CO., LTD. 2006-10-26 — — US disclosed
CN-1257891-C Nitrogenous five-membered ring compound TANABE SEIYAKU CO (JP) 2006-05-31 — — CN disclosed
US-20050054678-A1 Nitrogenous five-membered ring compounds TANABE SEIYAKU CO., LTD. (JP) 2005-03-10 — — US disclosed
CN-1468216-A Nitrogenous five-membered ring compound ������ҩ��ʽ���� 2004-01-14 — — CN disclosed
EP-1323710-A1 NITROGENOUS FIVE-MEMBERED RING COMPOUNDS Tanabe Seiyaku Co., Ltd. (JP) 2003-07-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090076005-A1 Kinase inhibitor compounds MAP3K1, MAP3K20, MAP3K2 KDM4E 1241/4885CYP2C19 4412/4885DKK1 1856/4885
US-20120115866-A1 KINASE INHIBITOR COMPOUNDS MAP3K1, MAP3K20, MAP3K2 KDM4E 1241/4885CYP2C19 4412/4885DKK1 1856/4885
US-20060241146-A1 Nitrogen-containing 5-membered ring compound ALK, SCO2, NPR1 KDM4E 2108/4885CYP2C19 851/4885DKK1 4862/4885
US-20050054678-A1 Nitrogenous five-membered ring compounds ALK, NPR1, SCO2 KDM4E 2135/4885CYP2C19 1102/4885DKK1 4845/4885
US-12509444-B2 Compounds and methods for CD73 modulation and indications therefor ENTPD5, ADORA1, ADORA2A KDM4E 3084/4885CYP2C19 2257/4885DKK1 396/4885
US-20230339937-A1 CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS HPGDS, PTGS1, PTGIS KDM4E 2711/4885CYP2C19 330/4885DKK1 4327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.