Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6453256 | 1.00 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3TRPV3ESR1 | |
| SCHEMBL6460286 | 0.91 | CYP2C9 (0.36) | CYP2C9ESR2 | |
| SCHEMBL6460295 | 0.91 | CYP2C9 (0.36) | CYP2C9ESR2 | |
| SCHEMBL6458709 | 0.90 | TRPV3 (0.32) | SLC6A2SLC6A4SLC6A3TRPV3 | |
| SCHEMBL6458703 | 0.90 | TRPV3 (0.32) | SLC6A2SLC6A4SLC6A3TRPV3 | |
| SCHEMBL6452454 | 0.89 | RAB9A (0.32) | CYP2C9 | |
| SCHEMBL6452450 | 0.89 | RAB9A (0.32) | CYP2C9 | |
| SCHEMBL6451460 | 0.88 | RAB9A (0.31) | CYP2C9 | |
| SCHEMBL6451466 | 0.88 | RAB9A (0.31) | CYP2C9 | |
| SCHEMBL6452326 | 0.87 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3TRPV3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |