Dimethylamine

Dimethylamine

SCHEMBL645332

CNC.c1ccc(-c2ccccc2P(C2CCCCC2)C2CCCCC2)cc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
NPSR1 Q6W5P4 3/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GAA P10253 2/20 0.38
TDP1 Q9NUW8 1/20 0.36
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
ROCK2 O75116 1/20 0.35
MAPT P10636 1/20 0.34
HTT P42858 2/20 0.34
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
PTGS2 P35354 1/20 0.33
CYP11B2 P19099 1/20 0.33
SLC6A2 P23975 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133189 0.93 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL29353025 0.93 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL1159030 0.93 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL5840557 0.92 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL1931350 0.92 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL33526641 0.92 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ANPSR1LMNA
Hydrochloric Acid SCHEMBL29639278 0.92 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL16694717 0.92 GAA (0.39) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL19469297 0.89 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL27516331 0.89 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ANPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230339937-A1 CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS SATO PHARMACEUTICAL CO., LTD. (JP) 2023-10-26 US disclosed
WO-2023113023-A1 AZAINDOLE DERIVATIVE INHIBITING H-PGDS 佐藤製薬株式会社 2023-06-22 WO disclosed
EP-4169575-A1 CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS Sato Pharmaceutical Co., Ltd. (JP) 2023-04-26 EP disclosed
EP-2614065-B1 SUBSTITUTED PYRAZOLO-QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS NERVIANO MEDICAL SCIENCES SRL (IT) 2017-04-19 EP disclosed
EP-1713789-B1 2-HALOFURYL/THIENYL-3-CARBOXAMIDES BAYER IP GMBH (DE) 2015-05-27 EP disclosed
EP-1628962-B1 Iodopyrazolyl carboxanilides BAYER IP GMBH (DE) 2014-10-01 EP disclosed
EP-1678142-B1 HEXYL CARBOXANILIDES AND THEIR USE FOR CONTROLLING UNDESIRABLE MICRO-ORGANISMS BAYER CROPSCIENCE AG (DE) 2014-10-01 EP disclosed
US-8541576-B2 Substituted pyrazolo-quinazoline derivatives as kinase inhibitors NERVIANO MEDICAL SCIENCES SRL (IT) 2013-09-24 US disclosed
EP-2614065-A1 SUBSTITUTED PYRAZOLO-QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS Nerviano Medical Sciences S.r.l. (IT) 2013-07-17 EP disclosed
US-20120190678-A1 SUBSTITUTED PYRAZOLO-QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS NERVIANO MEDICAL SCIENCES SRL (IT) 2012-07-26 US disclosed
WO-2005058839-A1 OPTICALLY ACTIVE CARBOXAMIDES AND USE THEREOF TO COMBAT UNDESIRABLE MICROORGANISMS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-06-30 WO disclosed
WO-2005042494-A1 ISOPENTYL CARBOXANILIDES FOR COMBATING UNDESIRED MICRO-ORGANISMS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-05-12 WO disclosed
WO-2005042493-A1 HEXYL CARBOXANILIDES AND THEIR USE FOR CONTROLLING UNDESIRABLE MICRO-ORGANISMS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-05-12 WO disclosed
WO-2004103953-A1 DIFLUOROMETHYLBENZANILIDES AND USE THEREOF FOR COMBATING MICRO-ORGANISMS, INTERMEDIATE PRODUCTS AND USE THEREOF BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2004-12-02 WO disclosed
WO-2004103975-A1 IODOPYRAZOLYL CARBOXANILIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2004-12-02 WO disclosed
US-20040204470-A1 Pyrazoylcarboxanilides as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2004-10-14 US disclosed
WO-2004072023-A2 OXATHIIN CARBOXAMIDE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2004-08-26 WO disclosed
WO-2004067515-A1 PYRAZOLYL CARBOXANILIDES FOR CONTROLLING UNWANTED MICROORGANISMS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2004-08-12 WO disclosed
EP-1414803-A1 PYRAZOLYLCARBOXANILIDES AS FUNGICIDES Bayer CropScience AG (DE) 2004-05-06 EP disclosed
WO-2003010149-A1 PYRAZOLYLCARBOXANILIDES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2003-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120190678-A1 SUBSTITUTED PYRAZOLO-QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS PIM1, PIM2, PIM3 ALDH1A1 3389/4885MEN1 4293/4885KMT2A 1550/4885
US-20040204470-A1 Pyrazoylcarboxanilides as fungicides CYP1A1, CYP1B1, CYP2E1 ALDH1A1 358/4885MEN1 1340/4885KMT2A 2799/4885
US-20230339937-A1 CONDENSED RING COMPOUNDS THAT INHIBIT H-PGDS HPGDS, PTGS1, PTGIS ALDH1A1 748/4885MEN1 4367/4885KMT2A 2511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.