SCHEMBL6454130

SCHEMBL6454130

C=COCCCNC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HPGD P15428 2/20 0.35
NPC1 O15118 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
CA3 P07451 2/20 0.35
CA5A P35218 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14501529 0.77 TSHR (0.47) LMNAALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL13660343 0.77 ALDH1A1 (0.45) LMNAALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL10030961 0.76 ZDHHC20 (0.53) LMNAALDH1A1HPGDNPC1MAPK1
SCHEMBL13660345 0.74 MEN1 (0.58) LMNAALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL13660337 0.74 MEN1 (0.58) LMNAALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL13660344 0.74 MEN1 (0.58) LMNAALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL14193170 0.73 KEAP1 (0.41) LMNAALDH1A1POLBHPGDNPC1
SCHEMBL14501533 0.73 TSHR (0.43) LMNAALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL17613225 0.73 MEN1 (0.57) LMNAALDH1A1MEN1KMT2ATSHR
SCHEMBL14008165 0.73 TSHR (0.47) LMNAALDH1A1SMN1; SMN2KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108641043-B Self-repairing graft copolymer based on hydrogen bond effect and preparation method thereof 武汉纺织大学 2021-02-26 CN disclosed
CN-108586676-B Heat-resistant graft copolymer and preparation method thereof 武汉纺织大学 2020-12-04 CN disclosed
US-20050113543-A1 Alpha, omega-allyl terminated linear poly(methacrylic acid) macromonomers for end-linked hydrogels and method of preparation MORNINGSIDE, COLUMBIA UNIVERSITY OF NY 2005-05-26 US disclosed
WO-2003101934-A1 α,φ-ALLYL TERMINATED LINEAR POLY(METHACRYLIC ACID) MACROMONOMERS FOR END-LINKED HYDROGELS AND METHOD OF PREPARATION THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2003-12-11 WO disclosed