Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454975 | 1.00 | KDM1A (0.34) | KDM1APTGS1PTGS2MAP1LC3BSLC6A2 | |
| SCHEMBL6454430 | 0.95 | PTGS2 (0.36) | KDM1APTGS1PTGS2MAP1LC3B | |
| SCHEMBL6454428 | 0.95 | PTGS2 (0.36) | KDM1APTGS1PTGS2MAP1LC3B | |
| SCHEMBL6454565 | 0.92 | — | — | |
| SCHEMBL6454561 | 0.92 | — | — | |
| SCHEMBL9165916 | 0.85 | MAP1LC3B (0.34) | KDM1APTGS1PTGS2MAP1LC3BHTR2A | |
| SCHEMBL9165328 | 0.85 | MAP1LC3B (0.34) | KDM1APTGS1PTGS2MAP1LC3BHTR2A | |
| SCHEMBL9252561 | 0.85 | MAP1LC3B (0.34) | KDM1APTGS1PTGS2MAP1LC3BHTR2A | |
| SCHEMBL6458485 | 0.84 | ESR2 (0.44) | — | |
| SCHEMBL6457093 | 0.84 | KDM1A (0.34) | KDM1AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |